Barrett's adenocarcinoma: Endoscopy in Minimally Invasive Curative Treatment

Abstract Text We present the case of a 62-year-old female patient with Barrett's esophagus (C5M6, Prague classification), referred for upper endoscopy due to iron-deficiency anemia. A flat lesion (Paris 0-IIa) measuring 22 mm was noted at the 6 o’clock position, with irregular disrupted pattern under narrow-band imaging. Biopsies confirmed well-differentiated tubular adenocarcinoma. CT revealed no locoregional or distant disease, and endoscopic ultrasound staged the lesion as T1aN0Mx. Endoscopic submucosal dissection was performed with tunneling technique for en bloc resection. Histopathology confirmed submucosal invasion (400 µm), clear margins, and no lymphovascular invasion. The patient is asymptomatic, under annual surveillance, and undergoing radiofrequency ablation [1] [2].

Video http://data.process.y-congress.com/ScientificProcess/Data//106/570/1428/e552b176-98b7-4358-9eef-d993ca5bdbdb/Uploads/16849_ESGE3.mp4

Publication History

Article published online:
27 March 2025

• References

• 1 Weusten B.. et al. Diagnosis and management of Barrett esophagus: European Society of Gastrointestinal Endoscopy (ESGE) Guideline Endoscopy. 2023 55.
• 2 Pimentel-Nunes P.. et al. Endoscopic submucosal dissection for superficial gastrointestinal lesions: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Update 2022. Endoscopy 2022; 54: 591-622