Invisible Polyps No More – The AI Revolution: A case-series of video examples

Colonoscopy for colorectal cancer screening is endoscopist dependent, with adenoma missed rates up to 30%. According to the literature, computer-aided detection (CADe) devices may improve adenoma detection rates (ADR) and polyp detection rates (PDR); however, the vast majority of studies showing superiority have compared CADe assisted and standard colonoscopy on different patient groups. Our study “Computer-Aided Detection Improves Adenoma Detection Rate for Screening Colonoscopy: A Prospective Tandem Study” (presented in Digestive Disease Week 2024) showed that CADe assisted colonoscopy (CAC) is superior to ultra-high-definition white light colonoscopy (WLC), when both interventions are performed on the same patient group, using a back-to-back tandem procedure (ADR – CAC: 28.2% vs WLC: 11.8%, p=0.007).

In this case-series, we will present twelve video examples of endoscopic detection and resection of polyps from cases that were included in our original study. We will show you ten video examples of sessile polyps that were completely invisible using WLC (Ultra HD – 4K – 4096 x 2160) but were immediately detected using CAC (Paris 0-IIb,<0.6mm). Histopathological examination of these polyps revealed three hyperplastic polyps, four serrated adenomas, and three adenomas. Furthermore, we will present two video examples of extremely small polyps (< 1 cm, Paris 0-IIa) in which histopathological examination showed in situ neoplasms. This can be an interactive presentation where the audience members will have the opportunity to share the original endoscopist’s point-of-view while using traditional WLC, and thus decide for themselves whether these polyps are truly invisible.

Publication History

Article published online:
27 March 2025