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Synlett 1996; 1996(1): 100-102
DOI: 10.1055/s-1996-5335
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Total Synthesis and Absolute Configuration of (-)-Sedacryptine

Eiji Akiyama, Masahiro Hirama*
  • *Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-77, Japan, Fax: 022-217-6566
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Publication Date:
31 December 2000 (online)

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Enantioselective synthesis of (-)-sedacryptine, a piperidine alkaloid, has been achieved via the double intramolecular conjugate additions or carbamate group and its absolute configuration was determined.

(-)-sedacryptine - piperidine alkaloid - intramolecular conjugate addition - carbamate - absolute configuration