Chiral Friedel-Crafts Alkylation of Aromatic Compounds Using Chiral Episulfonium Ions as Carbon Electrophiles
31 December 2000 (online)
The electrophilic aromatic substitution reaction by a chiral episulfonium ion, that works as a chiral carbenium ion equivalent, proceeds without loss of the enantiomeric purity. This reaction constitutes a convenient procedure for the preparation of chiral hydrocarbons bearing the aryl group at the asymmetric carbon atom with the predictable configuration.
Chiral episulfonium ion - Friedel-Crafts alkylation - Diarylethane