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Synlett 1998; 1998(1): 1-16
DOI: 10.1055/s-1998-1557
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Transition Metal Catalyzed Cycloisomerizations

Barry M. Trost* , Michael J. Krische
  • *Department of Chemistry, Stanford University, Stanford, CA 94305-5080 (USA); Fax (4 15) 7 25-02 59; E-mail: bmtrost@leland.stanford.edu
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Publication History

Publication Date:
31 December 2000 (online)

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Transformations that occur with complete atom economy minimize utilization of raw material and produce no waste and thus represent an upper limit of synthetic efficiency. Transition metal catalyzed cycloisomerizations represent a major class of atom economical reactions. Examples of the myriad of reaction types involving transition metal catalyses that comprise this class of chemical transformations are presented herein.

cycloisomerization - transition metal catalysis - macrocyclization - cyclization and atom economy

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