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Synlett 1998; 1998(3): 289-291
DOI: 10.1055/s-1998-1636
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Heteroaromatic Dithioacetals Part I: The Preparation of Unsymmetrical Dithioacetals from Heteroaromatic Thiols

Jacques Yves Gauthier* , Nicolas Zajac, Darrin L. Mayhew, Gregory J. Hughes, Evelyn Martins, Daniel Guay, Robert N. Young, Robert J. Zamboni
  • *Medicinal Chemistry Department, Merck Frosst Centre For Therapeutic Research, P.O. Box 1005, Pointe Claire-Dorval, Québec, Canada, H9R 4P8; E-mail: jacquesyves_gauthier@merck.com
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Publication Date:
31 December 2000 (online)

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The preparation of unsymmetrical dithioacetals derived from heteroaromatic thiols and alkyl thiols is described. Insights into the rich potential of this new class of thioacetals is exemplified with the conversion to various derivatives.

heteroaromatic thiols - aliphatic thiols - unsymmetrical dithioacetals