Characteristics of Sleep-Related Obstructive Respiratory Disturbances in Childhood

Sabine Scholle; Birgit Rieger; Grim Kemper; Ekkehard Seidler; Andrea Kemper; Sven Glaser; Gerhard Zwacka

doi:10.1055/s-2000-11531

Sleep and Breathing, Inhaltsverzeichnis

Sleep Breath 2000; 04(1): 0015-0020
DOI: 10.1055/s-2000-11531

Characteristics of Sleep-Related Obstructive Respiratory Disturbances in Childhood

Sabine Scholle, Birgit Rieger, Grim Kemper, Ekkehard Seidler, Andrea Kemper, Sven Glaser, Gerhard Zwacka

Center for Sleep Medicine and Pediatric Clinic (Schlafmedizinisches Zentrum und Kinderklinik), Robert Koch Hospital Apolda, Apolda, Thuringia, Germany

Abstract

ABSTRACT

Sleep-related obstructive respiratory disturbances in childhood differ significantly from the adult's obstructive sleep apnea syndrome (OSAS). In contrast to adults, in children with OSAS the disturbance of the macrostructure of sleep, the increase of the number of apneas and hypopneas, and the diminution of oxygen saturation are not so prominent. Restlessness of the sleep, as reflected by movement arousals together with cortical (electroencephalograph-recorded) arousals, is important. The combination of clinical symptoms and polysomnographic parameters is necessary to diagnose OSAS in children.

KEYWORD

obstructive sleep apnea syndrome (OSAS) - childhood - sleep structure - respiratory arousal

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Referenzen

REFERENCES

1 Guilleminault C, Stoohs R. Obstructive sleep apnea syndrome in children. Pediatrician . 1990; 17 46-51
2 Guilleminault C, Pelayo R. Sleep-disordered breathing in children. Ann Med . 1998; 30 350-356
3 Marcus C L. Clinical and pathophysiological aspects of obstructive sleep apnea in children. Pediatr Pulmonol Suppl . 1997; 16 123-124
4 Perkin R M, Downey R, Macquarrie J. Sleep-disordered breathing in infants and children. Respir Care Clin North Am . 1999; 5 395-426
5 Poets C F, Paditz E. Obstruktives Schlaf-Apnoe-Syndrom. Monatsschr Kinderheilkd . 1998; 146 826-836
6 Ward S L, Marcus C L. Obstructive sleep apnea in infants and young children. J Clin Neurophysiol . 1996; 13 198-207
7 Warwick J P, Mason D G. Obstructive sleep apnoea syndrome in children. Anaesthesia . 1998; 53 571-579
8 Marcus C L, Lutz J, Carroll J L, Bamford O. Arousal and ventilatory responses during sleep in children with obstructive sleep apnea. J Appl Physiol . 1998; 84 1926-1936
9 Garay S M, Rapoport D, Sorkin B. Regulation of ventilation in the obstructive sleep apnea syndrome. Am Rev Respir Dis . 1981; 124 451-457
10 Isono S, Shimada A, Utsugi M, Konno A, Nishino T. Comparison of static mechanical properties of the passive pharynx between normal children and children with sleep-disordered breathing. Am J Respir Crit Care Med . 1998; 157 1204-1212
11 Guilleminault C, Philip P, Robinson A. Sleep and neuromuscular disease: Bilevel positive airway pressure by nasal mask as a treatment for sleep disordered breathing in patients with neuromuscular disease. J Neurol Neurosurg Psychiatry . 1998; 65 225-232
12 Carroll J L, McColley S A, Marcus C L, Curtis S, Loughlin G M. Inability of clinical history to distinguish primary snoring from obstructive sleep apnea syndrome in children. Chest . 1995; 108 610-618
13 Stradling J R, Thomas G, Warley A RH, Williams P, Freeland A. Effect of adenotonsillectomy on nocturnal hypoxemia, sleep disturbance, and symptoms in snoring children. Lancet . 1990; 335 249-253
14 Gozal D. Morbidity in pediatric obstructive sleep apnea: How much do we really know?. Sleep Res Online . 1999; 2(suppl 1) 673
15 Singer L P, Saenger P. Complications of pediatric obstructive sleep apnea. Otolaryngol Clin North Am . 1990; 23 665-676
16 Guilleminault C, Pelayo R, Leger D, Clerk A, Bocian R C. Recognition of sleep-disordered breathing in children. Pediatrics . 1996; 98 871-882
17 Marcus C L, Lutz J, Hamer A, Smith P L, Schwartz A. Developmental changes in response to subatmospheric pressure loading of the upper airway. J Appl Physiol . 1999; 87 626-633
18 McNamara F, Issa F G, Sullivan C E. Arousal pattern following central and obstructive breathing abnormalities in infants and children. J Appl Physiol . 1996; 81 2651-2657
19 Scholle S, Kemper A, Glaser S, Rieger B, Zwacka G. Methodische Aspekte polysomnographischer Untersuchungen im Kindesalter II. Welche Parameter charakterisieren einen unruhigen Schlaf?. Somnologie . 1999; 3 26-30
20 Brouilette R T, Hanson D, David R. A diagnostic approach to suspected obstructive sleep apnea in children. J Pediatr . 1984; 105 10-14
21 Scholle S, Zwacka G. Sleep structure in children with OSA with and without nCPAP therapy. Sleep Res Online . 1999; 2(suppl 1) 442
22 McNamara F, Sullivan C E. Effects of nasal CPAP therapy on respiratory and spontaneous arousals in infants with OSA. J Appl Physiol . 1999; 87 889-896
23 Mograss M A, Ducharme F M, Brouilette R T. Movement/arousal description, classification, and relationsship to sleep apnea in children. Am J Respir Crit Care Med . 1994; 150 1690-1696
24 Scholle S, Kemper A, Glaser S, Rieger B, Zwacka G. Methodische Aspekte polysomnographischer Untersuchungen im Kindesalter I. Arm- und Beinbewegungen und EEG-Arousals als Kriterien der Schlafbewertung. Somnologie . 1998; 2 184-188
25 Berry R B, Gleeson K. Respiratory arousal from sleep: Mechanisms and significance. Sleep . 1997; 20 654-675
26 Marcus C L, Moreira G A, Bamford O, Lutz J. Response to inspiratory resistive loading during sleep in normal children and children with obstructive apnea. J Appl Physiol . 1999; l87 1448-1454