Endoscopy 2000; 32(7): 539-541
DOI: 10.1055/s-2000-3812
Case Report
Georg Thieme Verlag Stuttgart ·New York

Penetration by a Giant Gastric Ulcer Induced by a Nonsteroidal Anti-Inflammatory Drug

I. Shimizu 1 , T. Horie 2 , H. Inoue 2 , T. Oshima 2 , M. Fujimoto 2 , Y. Ozaki 2 , K. Yamamoto 2 , A. Iuchi 2 , S. Ito 1
  • 1 Second Dept. of Internal Medicine, School of Medicine, University of Tokushima, Tokushima, Japan
  • 2 Dept. of Internal Medicine, Miyoshi Prefectural Hospital, Tokushima, Japan
Further Information

Publication History

Publication Date:
31 December 2000 (online)

A patient presented with penetration by a giant gastric ulcer resulting from treatment with a nonsteroidal anti-inflammatory drug. A test for Helicobacter pylori proved negative. Treatment with a combination of an inhibitor of gastric acid secretion and prostaglandin substitution therapy with misoprostol resulted in closure of the perforation and cicatrization of the gastric ulcer without the need for laparotomy.


I. Shimizu, M.D.

Second Dept. of Internal Medicine Tokushima University School of Medicine

Kuramoto-cho Tokushima 770-8503 Japan

Fax: Fax:+ 81-886-33-9235

Email: E-mail:shimizui@clin.med.tokushima-u.ac.jp