PDF herunterladen
Synlett 2000; 2000(3): 345-346
DOI: 10.1055/s-2000-6525
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Preparation of New Magnesiated Functionalized Imidazoles and Antipyrines via an Iodine-Magnesium Exchange

Florian Dehmel* , Mohamed Abarbri, Paul Knochel
  • *Institut für Organische Chemie, Ludwig-Maximilians-Universität München, Butenandtstrasse 5-13, Building F, D-81377 München, Germany; Fax int. +89-21 80-76 80; E-mail: Paul.Knochel@cup.uni-muenchen.de
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
31. Dezember 2000 (online)

 als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

The iodine-magnesium exchange using i-PrMgBr allows the preparation of magnesiated 3-pyrazolin-5-ones (antipyrines) and functionalized imidazoles which after reaction with various electrophiles afford polyfunctional 5-membered heterocycles.

imidazoles - antipyrines - Grignard reagents - functionalized organometallics - iodine-magnesium exchange