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Synlett 2000; 2000(3): 339-340
DOI: 10.1055/s-2000-6539
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An Efficient Method for Cleavage of Epoxides with Aromatic Amines Catalysed by β-Cyclodextrin in Water

L. Rajender Reddy* , M. Arjun Reddy, N. Bhanumathi, K. Rama Rao
  • *Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad-500 007, India
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Publication Date:
31 December 2000 (online)

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β-Cyclodextrin catalyses for the first time the ring opening of epoxides with aromatic amines in water at room temperature to afford the corresponding β-amino alcohols in good yields.

epoxide - aromatic amine - β-cyclodextrin - water - β-amino alcohol