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Synlett 2001; 2001(5): 0627-0628
DOI: 10.1055/s-2001-13391
DOI: 10.1055/s-2001-13391
letter
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A Straightforward Synthesis of 4-Hydroxy-(E)-2-alkenoic Esters Mediated by SmI2
Further Information
Publication History
Publication Date:
31 December 2001 (online)
Coupling reactions of ketones with propiolate esters in intermolecular manner by SmI2 gave 4-hydroxy-(E)-2-alkenoic esters in THF-t-BuOH at 0 °C in moderate to good yields.
coupling reaction - SmI2 - intermolecular manner - propiolate ester - 4-hydroxy-(E)-2-alkenoic esters