Over the past two decades, endoscopic ultrasonography (EUS) has undergone a transition
from being a novel imaging technique to a clinical diagnostic test that is necessary
for the optimal management of gastrointestinal diseases. EUS has established itself
as an important diagnostic modality, mainly for the detection and staging of gastrointestinal
cancers. As EUS has become more widespread, research has gradually shifted towards
studies that explore the effect of EUS on patient management and outcome. These outcome
studies have examined the primary clinical applications of EUS, such as esophageal,
gastric, pancreatic, and colorectal cancer staging, as well as the role of EUS in
the diagnosis of inflammatory pancreatic diseases. Widespread use of EUS has recently
led to studies that examine complications associated with the performance of the procedure.
Endosonographers have continued efforts to define a clinical role for EUS in other
gastrointestinal diseases, such as portal hypertension. EUS-guided fine-needle aspiration
(FNA) is continuing to develop into a powerful diagnostic tool for the management
of lung cancer and other mediastinal diseases. New applications for EUS-FNA are also
emerging. Finally, investigators are continuing to explore the remaining frontier
of EUS-guided therapy.
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A. Chak, M.D.
Associate Professor of Medicine and Oncology · Case Western Reserve University · University
Hospitals of Cleveland
11100 Euclid Avenue · Cleveland, OH 44118 · USA
Fax: + 1-216-844-8011
eMail: axc22@po.cwru.edu