A Radical Carbon-carbon Bond Forming Reaction: Indium Mediated Radical Addition to β-Substituted Conjugated Alkenes in Aqueous Media

Abstract

Indium-mediated 1,4-addition of alkyl radical to β-substituted conjugated alkenes in aqueous media has been developed. The reaction affords 1,4-addition products to various α,β-enones regiospecifically in high isolated yields.

Key words

indium - radical reaction - addition reaction - alkene - alkyl halide

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