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Synlett 2002(6): 0871-0874
DOI: 10.1055/s-2002-31930
DOI: 10.1055/s-2002-31930
LETTER
© Georg Thieme Verlag Stuttgart · New YorkPalladium- or Nickel-Catalyzed Cross-Coupling of Organotitanium Reagents with Aryl Triflates and Halides
Further Information
Received
20 March 2002
Publication Date:
07 February 2007 (online)
Publication History
Publication Date:
07 February 2007 (online)
Abstract
The reaction of organotitanium reagents, methyltitanium triisopropoxide [MeTi(i-PrO)3] and phenyltitanium triisopropoxide [PhTi(i-PrO)3], with aryl triflates and halides proceeded in the presence of 1.0 mol% of palladium catalyst coordinated with (R*)-N,N-dimethyl-1-[(S*)-2-(diphenylphosphino)ferrocenyl]ethylamine [(R*)-(S*)-PPFA] in refluxing THF to give a quantitative yield of the corresponding cross-coupling products.
Key words
cross-coupling - organotitanium - palladium catalyst - aryl triflate - aryl halide
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