Semin Hear 2002; 23(3): 201-208
DOI: 10.1055/s-2002-34457
Copyright © 2002 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Considerations in the Clinical Evaluation of Auditory Neuropathy/Auditory Dys-Synchrony

Linda J. Hood, Charles I. Berlin, Thierry Morlet, Shanda Brashears, Kelly Rose, Sonya Tedesco
  • Kresge Hearing Research Laboratory, Department of Otolaryngology and Biocommunication, Louisiana State University Health Sciences Center, New Orleans, Louisiana
Further Information

Publication History

Publication Date:
02 October 2002 (online)

ABSTRACT

Auditory neuropathy/auditory dys-synchrony is characterized by normal outer hair cell function and dys-synchronous neural responses. Otoacoustic emissions, auditory brainstem responses, and middle-ear muscle reflexes are valuable methods for clinical differentiation. Patients with auditory neuropathy/auditory dys-synchrony characteristically demonstrate difficulty understanding speech, particularly in situations with competing stimuli. Patients vary widely in auditory and other characteristics, and several possible underlying mechanisms are thought to be responsible for this hearing disorder.

REFERENCES

  • 1 Berlin C, Hood L, Rose K. On renaming auditory neuropathy as auditory dys-synchrony.  Audiol Today . 2001;  13 15-17
  • 2 Berlin C I, Li L, Hood L J. Auditory neuropathy/dys-synchrony: after the diagnosis, then what?.  Semin Hear . 2002;  [this vol pp-pp]
  • 3 Worthington D W, Peters J F. Quantifiable hearing and no ABR: paradox or error?.  Ear Hear . 1980;  1 281-285
  • 4 Kraus N, Özdamar Ö, Stein L, Reed N. Absent auditory brainstem response: peripheral hearing loss or brain stem dysfunction?.  Laryngoscope . 1984;  94 400-406
  • 5 Starr A, McPherson D, Patterson J. Absence of both auditory evoked potentials and auditory percepts depending on timing cues.  Brain . 1991;  114 1157-1180
  • 6 Berlin C I, Hood L J, Cecola R P, Jackson D F, Szabo P. Does type I afferent neuron dysfunction reveal itself through lack of efferent suppression?.  Hear Res . 1993;  65 40-50
  • 7 Gravel J S, Stapells D R. Behavioral, electrophysiologic and otoacoustic measures from a child with auditory processing dysfunction: case report.  J Am Acad Audiol . 1993;  4 412-419
  • 8 Gorga M P, Stelmachowicz P G, Barlow S M, Brookhouser P E. Case of recurrent, reversible, sudden sensorineural hearing loss in a child.  J Am Acad Audiol . 1995;  6 163-172
  • 9 Sininger Y S, Hood L J, Starr A, Berlin C I, Picton T W. Hearing loss due to auditory neuropathy.  Audiol Today . 1995;  7 10-13
  • 10 Starr A, Picton T W, Sininger Y S, Hood L J, Berlin C I. Auditory neuropathy.  Brain . 1996;  119 741-753
  • 11 Berlin C I, Bordelon J, St John P. Reversing click polarity may uncover auditory neuropathy in infants.  Ear Hear . 1998;  19 37-47
  • 12 Rance G, Beer D E, Cone-Wesson B. Clinical findings for a group of infants and young children with auditory neuropathy.  Ear Hear . 1999;  20 238-252
  • 13 Dallos P. The Auditory Periphery.  New York: Academic Press 1993
  • 14 Berlin C I, Hood L J, Hurley A, Wen H. Contralateral suppression of otoacoustic emissions: an index of the function of the medial olivocochlear system.  Otolaryngol Head Neck Surg . 1994;  100 3-21
  • 15 Yellin M W, Jerger J, Fifer R C. Norms for disproportionate loss in speech intelligibility.  Ear Hear . 1989;  10 231-234
  • 16 Collet L, Kemp D T, Veuillet E. Effect of contralateral auditory stimuli on active cochlear micro-mechanical properties in human subjects.  Hear Res . 1990;  43 251-262
  • 17 Berlin C I, Hood L J, Hurley A, Wen H, Kemp D T. Binaural noise suppresses click-evoked otoacoustic emissions more than ipsilateral or contralateral noise.  Hear Res . 1995;  87 96-103
  • 18 Hood L J, Berlin C I, Hurley A, Cecola R P, Bell B. Contralateral suppression of click-evoked otoacoustic emissions: intensity effects.  Hear Res . 1996;  101 113-118
  • 19 Berlin C I, Hood L J, Hurley A, Wen H. Hearing aids: only for hearing-impaired patients with abnormal otoacoustic emissions. In: Berlin CI, ed. Hair Cells and Hearing Aids San Diego: Singular Publishing Group 1996: 99-112
  • 20 Hood L J, Berlin C I. Efferent suppression in patients with auditory neuropathy. In: Sininger YS, Starr A, eds. Auditory Neuropathy: A New Perspective on a Hearing Disorder San Diego: Singular Publishing Group 2001: 183-202
  • 21 Hirsh I J. The influence of interaural phase on interaural summation and inhibition.  J Acoust Soc Am . 1948;  20 536-544
  • 22 Licklider J CR. The influence of interaural phase relations upon the masking of speech by white noise.  J Acoust Soc Am . 1948;  20 150-159
  • 23 Deltenre P, Mansbach A L, Bozet C, Clercx A, Hecox K E. Auditory neuropathy: a report on three cases with early onsets and major neonatal illnesses.  Electroencephalogr Clin Neurophysiol . 1997;  104 17-22
  • 24 Stein L K, Tremblay K, Pasternak J, Banerjee S, Lindemann K. Auditory brainstem neuropathy and elevated bilirubin levels.  Semin Hear . 1996;  17 197-213
  • 25 Starr A, Sininger Y S, Pratt H. The varieties of auditory neuropathy.  J Basic Clinic Physiol Pharmacol . 2000;  11 215-230
  • 26 Simmons J, Beauchaine K I. Auditory neuropathy: case study with hyperbilirubinemia.  J Am Acad Audiol . 2000;  11 337-347
  • 27 Berlin C, Hood L, Morlet T. The search for auditory neuropathy patients and connexin 26 patients in schools for the deaf.  ARO Abstr . 2000;  23 23-24
  • 28 Starr A, Sininger Y, Winter M. Transient deafness due to temperature-sensitive auditory neuropathy.  Ear Hear . 1998;  19 169-179
  • 29 Deol M S, Kocher W. A new gene for deafness in the mouse.  Heredity . 1958;  12 463-466
  • 30 Bussoli T J, Kelly A, Steel P. Localization of the bronx waltzer (bv) deafness gene to mouse chromosome 5.  Mamm Genome . 1997;  10 714-717
  • 31 Amatuzzi M G, Northrup C, Liberman M C. Selective inner hair cell loss in premature infants and cochlea pathological patterns from neonatal intensive care unit autopsies.  Arch Otolaryngol Head Neck Surg . 2001;  127 629-636
  • 32 Lee J SM, McPherson B, Yuen K CP, Wong L LN. Screening for auditory neuropathy in a school for hearing impaired children.  Int J Pediatr Otolaryngol . 2001;  61 39-46