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Endoscopy 2003; 35(3): 219-222
DOI: 10.1055/s-2003-37258
Case Report

© Georg Thieme Verlag Stuttgart · New York

Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Melanoma Metastatic to the Pancreas: Report of Two Cases and Review

J.  M.  DeWitt1 , J.  Chappo1 , S.  Sherman1
  • 1Indiana University Medical Center, Indianapolis, Indiana, USA
Further Information

Publication History

Submitted: 24 April 2002

Accepted after Revision: 25 July 2002

Publication Date:
13 February 2003 (online)

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Malignant melanoma is a neoplasm which originates from melanocytes. Surgical exploration for abdominal metastases of cutaneous melanoma reveals pancreatic metastases in 16 % of patients which is usually accompanied by other intra-abdominal spread. Endoscopic ultrasound (EUS) and EUS-guided fine-needle aspiration (EUS-FNA) of primary and metastatic pancreatic masses have already been described. We report the first use of EUS-FNA for the diagnosis of malignant melanoma metastatic to the pancreas. As our cases illustrate, these lesions may present as either cystic or solid pancreatic masses. Preparation of a cell block from the FNA aspirate and use of immunostaining may help to obtain the diagnosis. Despite thorough examination of the skin and mucous membranes, however, a primary site might not be found in these patients.

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J. M. DeWitt, M.D.

Department of Medicine · Division of Gastroenterology · Indiana University Medical Center

550 N. University Blvd. · UH 4100 · Indianapolis, IN 46202-5121 · USA ·

Fax: + 1-317-278-8144

Email: jodewitt@iupui.edu

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