Endoscopy 2003; 35(6): 521-525
DOI: 10.1055/s-2003-39663

© Georg Thieme Verlag Stuttgart · New York

Nonspecific Ulcers of the Colon

J.  E.  Losanoff1 , B.  W.  Richman1 , J.  R.  Foerst1 , A.  D.  Griesemer1 , G.  M.  Mundis1 , J.  W.  Jones1
  • 1Dept. of Surgery, University of Missouri-Columbia School of Medicine, Columbia, Missouri, USA
Further Information

Publication History

Submitted 22 July 2002

Accepted after Revision 27 November 2002

Publication Date:
03 June 2003 (online)

Nonspecific colonic ulcers (NSCUs) are rare and potentially life-threatening lesions of unknown etiology; the diagnosis is based on histologic findings showing nonspecific inflammatory changes. The condition's variable symptoms can include nonspecific abdominal discomfort, gastrointestinal bleeding, perforation, and peritonitis. Radiologic imaging can be helpful in locating the lesions, but colonoscopy facilitates early definitive diagnosis and aggressive treatment. The potential of NSCUs to recur is currently unknown, and morbidity rates remain high. Long-term colonoscopic follow-up may improve the prognosis.


J. W. Jones, M.D., Ph. D.

Dept. of Surgery · M580 Health Sciences Center · University of Missouri-Columbia School of Medicine

One Hospital Drive · Columbia, MO 65212 · USA

Fax: + 1-573-884-4585 ·

Email: JonesJW@health.missouri.edu