Diagnostik fokaler Leberläsionen: CT, MRT, PET etc.

Zusammenfassung

Fokale Leberläsionen sind unabhängig vom Vorhandensein eines Malignoms ein häufiger Befund. Für ein eventuelles therapeutisches Management ist es dabei erforderlich, die Läsionen eindeutig zu identifizieren und zu charakterisieren. Zur nicht-invasiven Diagnostik stehen die Sonographie, Computertomographie (CT), Magnetresonanztomographie (MRT) und nuklearmedizinische Verfahren zur Verfügung. Die modernen chirurgischen wie auch minimalinvasiven ablativen Verfahren erfordern eine hohe diagnostische Präzision, die insbesondere von der CT und MRT gewährleistet wird. Darüber hinaus gewinnt die Positronenemissionstomographie (PET) gerade beim Staging und der Therapiekontrolle zunehmend an Bedeutung, was umso mehr für die kombinierten PET-CT Scanner gilt, die die hohe Sensitivität der PET mit der Ortsauflösung der CT vereinen.

Bei der Abklärung fokaler Leberläsionen müssen neben der Leistungsfähigkeit der einzelnen Untersuchungsmethoden das Spektrum möglicher Läsionen im Kontext der jeweiligen Grunderkrankung des Patienten berücksichtigt werden.

Abstract

Independently from the presence of a malignant disease focal hepatic lesions are a common finding. For a potential therapeutical management it is mandatory to identify and characterize precisely the lesions. For non-invasive diagnostics ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and nuclear scintigraphy are available. Current surgical and minimally invasive ablative techniques necessitate a high diagnostic precision, maintained especially by CT and MRI. Moreover, positron emission tomography (PET) yields increasingly importance mainly in staging and therapy control what is also true for the new combined PET-CT scanners which combine the high sensitivity of PET with the high spatial resolution of CT.

In the work-up of focal hepatic disease the potential of the diverse imaging modalities as well as the spectrum of the various lesions together with the findings of the underlying disease of the patient has to be considered.

Schlüsselwörter

Fokale Leberläsionen - Sonographie - CT - MRT - PET

Key words

Focal hepatic disease - ultrasound - CT - MRI - PET

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