Synthesis of Dendrimer-Supported Prolinols and Their Application in Enantioselective Reduction of Ketones

Guang-yin Wang; Xin-yuan Liu; Gang Zhao

doi:10.1055/s-2006-926253

LETTER

Synthesis of Dendrimer-Supported Prolinols and Their Application in Enantioselective Reduction of Ketones

Guang-yin Wang, Xin-yuan Liu, Gang Zhao*
Laboratory of Modern Synthetic Organic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin lu, Shanghai 200032, P. R. of China
Fax: +86(21)64166128; e-Mail: zhaog@mail.sioc.ac.cn;

Abstract

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Abstract

Optically active dendritic amino alcohols were synthesized and applied to catalyze the enantioselective borane reduction of various ketones with good yield and high enantiomeric excesses.

Key words

dendrimer-supported - asymmetric reduction - amino alcohol

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References

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