EUS-guided celiac block and neurolysis
18 September 2006 (online)
Abdominal pain related to pancreatic cancer or chronic pancreatitis can be a disabling and difficult symptom to treat for patients, their families, and physicians. Pharmacologic therapy with nonsteroidal anti-inflammatory drugs is usually ineffective. Opiate analgesics may not be well tolerated and can lead to dependence. Endoscopic ultrasound-guided celiac plexus block offers a potential adjunct treatment for pain control.
- 1 Wiersema M J, Wiersema L M. Endosonography-guided celiac plexus neurolysis. Gastrointest Endosc. 1996; 44 656-662
- 2 Copping J, Willix R. Palliative chemical splanchnicectomy. Arch Surg. 1969; 98 418-423
- 3 Wong G Y, Sakorafas G H, Tsiotos G G, Sarr M G. Palliation of pain in chronic pancreatitis: use of neural blocks and neurotomy. Surg Clin North Am. 1999; 79 873-893
- 4 Eisenberg E, Carr D B, Chalmers T C. Neurolytic celiac plexus block for treatment of cancer pain: a meta-analysis. Anesth Analg. 1995; 80 290-295
- 5 Gunaratnam N T, Sarma A V, Norton I D. et al . A prospective study of EUS-guided celiac plexus neurolysis for pancreatic cancer pain. Gastrointest Endosc. 2001; 54 316-324
- 6 Faigel D O, Veloso K M, Long W B, Kochman M L. Endosonography-guided celiac plexus injection for abdominal pain due to severe chronic pancreatitis. Am J Gastroenterol. 1996; 91 1675
- 7 Gress F, Schmitt C. A prospective randomized comparison of endoscopic ultrasound- and computed tomography-guided celiac plexus block for managing chronic pancreatitis pain. Am J Gastroenterol. 1999; 94 872-874
- 8 Gress F, Schmitt C. Endoscopic ultrasound-guided celiac plexus block for managing abdominal pain associated with chronic pancreatitis: a prospective single center experience. Am J Gastroenterol. 2001; 96 409-416
- 9 Davies D D. Incidence of major complications of neurolytic coeliac plexus block. J R Soc Med. 1993; 86 224-266
D. Collins, M. D.
Division of Gastroenterology, Hepatology, and Nutrition · University of Florida Health Science Center
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