Endoscopy 2006; 38(10): 1011-1015
DOI: 10.1055/s-2006-944779
Original article
© Georg Thieme Verlag KG Stuttgart · New York

A novel double-channel therapeutic endoscope (“R-scope”) facilitates endoscopic submucosal dissection of superficial gastric neoplasms

J.  Yonezawa1 , M.  Kaise1 , K.  Sumiyama1 , K.  Goda1 , H.  Arakawa1 , H.  Tajiri1, 2
  • 1Department of Endoscopy, The Jikei University School of Medicine, Tokyo, Japan
  • 2Department of Gastroenterology and Hepatology, The Jikei University School of Medicine, Tokyo, Japan
Further Information

Publication History

Submitted 30 March 2006

Accepted after revision 3 July 2006

Publication Date:
20 October 2006 (online)

Background and study aim: Endoscopic submucosal dissection (ESD) is a new and radical treatment for superficial gastrointestinal neoplasms that provides high rates of en bloc resection compared with treatment by conventional mucosal resection. However, ESD is a complex procedure that is associated with long operating times and a higher complication rate. This feasibility study assessed the use of a novel double-channel therapeutic endoscope for performing en-bloc ESD in order to assess whether the procedure time could be shortened.
Patients and methods: The therapeutic endoscope we used (the “R-scope”) is equipped with a multibending system and has two movable instrument channels: one moves a grasping forceps vertically for lesion countertraction; the other swings a cutting knife horizontally for dissection. Twenty consecutive patients (18 men, 2 women; mean age 63 years, range 54 - 80 years) with superficial gastric neoplasms in the distal two-thirds of the stomach underwent resection of their tumor by ESD using the R-scope. Forty size- and location-matched gastric neoplasms resected by conventional ESD were reviewed retrospectively for the purposes of comparison.
Results: The rates of curative en-bloc resection, complications, and local recurrence using the two ESD methods were comparable. The mean ± SD operating time was significantly shorter for ESD using the R-scope than for conventional ESD (57.9 ± 29.7 minutes vs. 92.8 ± 58.9 minutes, P = 0.016).
Conclusion: The R-scope appears to shorten the operating time of ESD with comparable efficacy and complication rates.

References

  • 1 Ono H, Kondo H, Gotoda T. et al . Endoscopic mucosal resection for treatment of early gastric cancer.  Gut. 2001;  48 225-229
  • 2 Ohkuwa M, Hosokawa K, Boku N. et al . New endoscopic treatment for intramucosal gastric tumors using an insulated-tip diathermic knife.  Endoscopy. 2001;  33 221-226
  • 3 Yamamoto H, Sekine Y, Higashizawa T. et al . Successful en bloc resection of a large superficial gastric cancer by using sodium hyaluronate and electrocautery incision forceps.  Gastrointest Endosc. 2001;  54 629-632
  • 4 Miyamoto S, Muto M, Hamamoto Y. et al . A new technique for endoscopic mucosal resection with an insulated-tip electrosurgical knife improves the completeness of resection of intramucosal gastric neoplasms.  Gastrointest Endosc. 2002;  55 576-581
  • 5 Yamamoto H, Kawata H, Sunada K. et al . Success rate of curative endoscopic mucosal resection with circumferential mucosal incision assisted by submucosal injection of sodium hyaluronate.  Gastrointest Endosc. 2002;  56 507-512
  • 6 Miyashita M, Tajiri T, Maruyama H. et al . Endoscopic mucosal resection scissors for the treatment of early gastric cancer.  Endoscopy. 2003;  35 611-612
  • 7 Rösch T, Sarbia M, Schumacher B. et al . Attempted endoscopic en bloc resection of mucosal and submucosal tumors using insulated-tip knives: a pilot series.  Endoscopy. 2004;  36 788-801
  • 8 Yamamoto H, Kawata H, Sunada K. et al . Successful en-bloc resection of large superficial tumors in the stomach and colon using sodium hyaluronate and small-caliber-tip transparent hood.  Endoscopy. 2003;  35 690-694
  • 9 Nakayoshi T, Tajiri H, Sasaki H. et al . Magnifying endoscopy combined with narrow band imaging system for early gastric cancer: correlation of vascular pattern with histopathology (including video).  Endoscopy. 2004;  36 1080-1084
  • 10 Tajiri H, Matsuda K, Fujisaki J. What can we see with the endoscope? Present status and future perspectives.  Dig Endosc. 2002;  14 131-137
  • 11 Fujishiro M, Yahagi N, Omata M. et al . Successful outcomes of a novel endoscopic treatment for GI tumors: endoscopic submucosal dissection with a mixture of high-molecular-weight hyaluronic acid, glycerin, and sugar.  Gastrointest Endosc. 2006;  63 243-249
  • 12 Oyama T, Kikuchi Y. Aggressive endoscopic mucosal resection in the upper GI tract - hook knife EMR method.  Minim Invasive Ther Allied Technol. 2002;  11 291-295
  • 13 Isshi K, Tajiri H, Fujisaki J. et al . The effectiveness of a new multibending scope for endoscopic mucosal resection.  Endoscopy. 2004;  36 294-297
  • 14 Sumiyama K, Kaise M, Tajiri H. et al . Combined use of a magnifying endoscope with a narrow band imaging system and a multibending endoscope for en bloc EMR of early stage gastric cancer.  Gastrointest Endosc. 2004;  60 79-84
  • 15 Sasaki T, Yamaguchi T, Nakajima S. et al .Therapeutic options and indication for gastric cancer. In: Japanese Gastric Cancer Association (eds) 2nd edn. Tokyo; Kanehara-shuppan 2004: 8-26
  • 16 Eguchi T, Gotoda T, Oda I. et al . Is endoscopic one-piece mucosal resection essential for early gastric cancer?.  Dig Endosc. 2003;  15 113-116
  • 17 Gotoda T, Ono H, Oda I. et al . The importance of histological evaluation and the necessity of one-piece resection for endoscopic gastric mucosal resection [in Japanese with English abstract].  Stomach Intest (Tokyo). 2002;  37 1145-1154
  • 18 Kakushima N, Yahagi N, Omata M. et al . Efficacy and safety of endoscopic submucosal dissection for tumors of the esophagogastric junction.  Endoscopy. 2006;  38 170-174
  • 19 Gotoda T, Yanagisawa A, Sasako M. et al . Incidence of lymph node metastasis from early gastric cancer: estimation with a large number of cases at two large centers.  Gastric Cancer. 2000;  3 219-225

M. Kaise, M. D.

Department of Endoscopy

The Jikei University School of Medicine · 3-25-8 Nishi Shinbashi · Minato-ku · Tokyo 103-8461 · Japan

Fax: +81-3-5438-8380

Email: kaise@jikei.ac.jp

    >