ABSTRACT
A new experimental model is presented, using isohistogenic Lewis rats and microsurgical
techniques. Transplantation of the head and forelimbs of the infantile rat was done
to the groin of an adult rat. The goal was to study the effects of ischemia on brain
tissue. This model also proved useful for other experiments in studies of facial and
cranial bone growth.
The model presented proved efficient for the study goals, and long-term experiments
were possible. The maximum ischemia time tolerated by brain tissue was found to be
somewhere between 60 min and 120 min.
