Mucoepidermoid Carcinoma of the Esophagus: Report of Two Cases and Review of the Literature

K. Sasajima; M. Watanabe; K. Takubo; A. Takai; K. Yamashita; M. Onda

doi:10.1055/s-2007-1012820

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Endoscopy 1990; 22(3): 140-143
DOI: 10.1055/s-2007-1012820

Mucoepidermoid Carcinoma of the Esophagus: Report of Two Cases and Review of the Literature

K. Sasajima¹ , M. Watanabe¹ , K. Takubo² , A. Takai¹ , K. Yamashita¹ , M. Onda¹

¹First Department of Surgery, Nippon Medical School, Tokyo
²Department of Pathology, Saitama Cancer Center, Saitama, Japan

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Publication Date:
17 March 2008 (online)

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Summary

The clinicopathological manifestation of mucoepidermoid carcinoma of the esophagus are reported in two cases. Barium swallow and endoscopy revealed infiltrating and constricting appearances. The tumors were grossly indurated, with or without ulceration. Histologically, the tumors were composed of a mixture of glandular cells which contained signet ring cells and squamous cells. In two cases, the tumor cells invaded into the adventitia, with lymph node metastasis. Two patients died of widespread metastasis within 1 year after operation.

Our results and previous reports suggest that mucoepidermoid carcinoma of the esophagus is extremely aggressive and has a poor prognosis.

Key words:

Mucoepidermoid carcinoma - Esophagus - Signet ring cell - Prognosis