Endoscopy 2007; 39(5): 423-427
DOI: 10.1055/s-2007-966237
Original article

© Georg Thieme Verlag KG Stuttgart · New York

Endoscopic submucosal dissection for rectal tumors

Y.  Onozato1 , S.  Kakizaki2 , H.  Ishihara1 , H.  Iizuka1 , N.  Sohara2 , S.  Okamura2 , M.  Mori2 , H.  Itoh3
  • 1Center of Gastroenterology, Maebashi Red Cross Hospital, Maebashi, Gunma, Japan
  • 2Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
  • 3Department of Pathology, Maebashi Red Cross Hospital, Maebashi, Gunma, Japan
Further Information

Publication History

submitted 4 July 2006

accepted after revision 4 October 2006

Publication Date:
13 March 2007 (online)

Background and study aim: Endoscopic submucosal dissection (ESD) has recently been developed for one-piece resection of gastric tumors. In order to improve patients’ quality of life, it may be desirable to use the same technique for rectal tumors.

Methods: 35 consecutive patients with rectal tumors were enrolled. ESD was carried out using the same technique as for the stomach. The efficacy, technical feasibility, operation time, complications, and follow-up results were assessed.

Results: The mean size of the epithelial tumors was 26.2 ± 14.0 mm, and the rates of one-piece resection and one-piece resection with tumor-free margins were 73.3 % (22 of 30) and 70.0 % (21 of 30), respectively. The median operation time was 70 min (range 8 - 360 min). All five carcinoid tumors were completely resected. No patient needed blood transfusion or had the complication of problematic bleeding. Perforation during ESD occurred in one patient (2.9 %), who was managed with conservative medical treatment after endoscopic closure of the perforation. Excluding seven patients, who either underwent additional surgery or whose follow-up period was less than 1 year, all 23 patients with epithelial tumors were free of recurrence during a mean follow-up period of 25.7 months (range 12 - 53 months).

Conclusions: ESD was thus found to be feasible for the treatment of rectal tumors, with promising results although the follow-up periods were short. ESD may therefore be indicated for rectal tumors which are not resectable en bloc by conventional procedures, in order to improve the patients’ quality of life.

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S. Kakizaki, MD PhD

Department of Medicine and Molecular Science

Gunma University Graduate School of Medicine

3-39-15 Showa-machi

Maebashi, Gunma 371-8511

Japan

Fax: +81-27-220-8136

Email: kakizaki@showa.gunma-u.ac.jp

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