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DOI: 10.1055/s-2007-966319
© Georg Thieme Verlag KG Stuttgart · New York
Metastatic malignant melanoma of the small intestine: capsule endoscopic appearance
Publication History
Publication Date:
05 July 2007 (online)

Capsule enteroscopy (CE) can identify primary [1] and metastatic intestinal melanoma, as previously described [2] and illustrated with surgical and histological verification [3]. However, capsule enteroscopic identification of the characteristic coal-black appearance of malignant melanoma has not been described previously in intestinal tumors.
A 56-year-old man receiving dendritic cell-based therapy for metastatic malignant melanoma presented with anemia and black stools. Abdominal computer tomography suggested peritoneal carcinomatosis. There were no clinical or radiological signs of intestinal obstruction. Gastroscopy and colonoscopy were normal. CE revealed a localized area with whitish tissue and characteristic coal-black, sharply demarcated circular areas, consistent with metastatic melanoma. This area was located in the ileum, centrally in the abdomen, after 6 hours 19 minutes ([Figure 1], Video 1). Because of the disseminated disease and the absence of obstructive symptoms, the dendritic cell-based therapy was continued without surgical intervention. The patient passed away 2 months later.
Figure 1 Capsule endoscopic appearance of a metastatic malignant melanoma in the small intestine.
Video 1 Capsule endoscopic appearance of a metastatic malignant melanoma in the small intestine.
online content including video sequences viewable at:
www.thieme-connect.de/ejournals/abstract/endoscopy/doi/
Endoscopy_UCTN_Code_CCL_1AC_2AC
References
- 1 Kruger S, Noack F, Blochle C, Feller A C. Primary malignant melanoma of the small bowel: a case report and review of the literature. Tumori. 2005; 91 73-76
- 2 Bailey A A, Debinsky H S, Appleyard M N. et al . Diagnosis and outcome of small bowel tumors found by capsule endoscopy: a three-center Australian experience. Am J Gastroenterol. 2006; 101 2237-2243
- 3 Lykke J, Hansen M B, Ovesen H, Meisner S. Capsule endoscopy detection of metastasis of a malignant melanoma in the small intestine. Ugeskr Læger. 2006; 168 3533-3534
S. Adamsen, MD 
         Department of Gastrointestinal Surgery
         
         Copenhagen University Hospital Herlev
         
         75, Herlev Ringvej
         
         DK-2730 Herlev
         
         Denmark
         
         Fax: +45-4488-4009
         
         Email: sven.adamsen@dadlnet.dk
         
         
 
     
      
    