Semin Reprod Med 2007; 25(2): 131-133
DOI: 10.1055/s-2007-970052
Copyright © 2007 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Reproductive Performance after Ectopic Pregnancy

John E. Buster1 , Stephan Krotz2
  • 1Professor of Obstetrics and Gynecology, Director, Division of Reproductive Endocrinology and Infertility, Baylor College of Medicine, Houston, Texas
  • 2Fellow in Reproductive Endocrinology and Infertility, Division of Reproductive Endocrinology and Infertility, Baylor College of Medicine, Houston, Texas
Further Information

Publication History

Publication Date:
22 March 2007 (online)


Reproductive performance may be an important variable in treatment selection for unruptured ectopic pregnancy. The impact of treatment choice on reproductive performance is not known. We searched the literature and then tabulated published case reports on laparoscopic salpingostomy, multiple-dose methotrexate, single-dose methotrexate, and expectant management. From this analysis, we are unable to conclude any clinically detectable differences in the efficacy of these four most common treatments for unruptured ectopic pregnancy. Even more recent reports using life tables are inconclusive because the studies are not randomized. We conclude that concern for long-term reproductive performance should not be a factor in selecting between any of these four commonly used treatments for unruptured ectopic pregnancy.


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John E BusterM.D. 

Division of Reproductive Endocrinology and Infertility, Baylor College of Medicine

1709 Dryden, Suite 1100 Houston, TX 77030