ABSTRACT
Hydrosalpinx is a common condition among women of reproductive age. It is related
to low pregnancy rates in the settings of in vitro fertilization-embryo transfer programs.
Such low rates are not yet well understood, and may be due to poor endometrial receptivity
and abnormal expression of key molecules in the endometrium that are important for
implantation. The available data on the inflammatory response, endometrial blood flow,
integrins, leukemia inhibitory factor, matrix metalloproteinases, and homeobox gene
A10 expression in the presence of hydrosalpinx are reviewed. In addition, the evidence
for treatment options to improve pregnancy rates is also discussed.
KEYWORDS
Hydrosalpinx - endometrium
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Ricardo Francalacci SavarisM.D.
Department of Obstetrics and Gynecology, University of San Francisco
505 Parnassus Ave., M1496, Box 0.132, San Francisco, CA 94143-013
Email: rsavaris@hcpa.ufrgs.br