ABSTRACT
Polycystic ovary syndrome (PCOS) is a common condition in women with reproductive
age associated with reproductive and metabolic dysfunction. Treatment has traditionally
focused on fertility and hormonal therapy. However, obesity, central obesity, and
insulin resistance (IR) are strongly implicated in its etiology, and improving these
factors has become a treatment target in PCOS. Lifestyle modification programs with
an emphasis on behavioral management and dietary and exercise interventions have been
successful in reducing the risk of diabetes and the metabolic syndrome in the general
population and improving reproductive and metabolic features in PCOS, although as
yet there is limited evidence for specific dietary and exercise approaches and guidelines
for use in PCOS and requires further investigation. The use of antiobesity pharmacologic
agents and bariatric surgery has been recently studied in PCOS and may offer additional
treatment options for the future. Future research should focus on the optimal dietary
strategies and exercise regimens for PCOS treatment and the relative efficacy and
appropriate use of lifestyle management versus antiobesity pharmacologic agents and
surgery.
KEYWORDS
Polycystic ovary syndrome - diet - weight loss - exercise
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Lisa J MoranPh.D.
The Jean Hailes Foundation for Women's Health, Monash Institute for Public Health
Research, Monash Medical Centre
Locked bag 29, Clayton Road, Clayton, Victoria, 3168, Australia
Email: lisa.moran@yahoo.com.au
