Multifocal Nodular Lymphoid Hyperplasia of the Lung Differently Identified by ¹⁸F-Fluorodeoxyglucose Positron Emission Tomography (FDG‐PET)

Abstract

Nodular lymphoid hyperplasia (NLH) is a rare lung disease classified as a non-neoplastic pulmonary lymphoid lesion. It is believed that 36 % of cases present with multifocal lesions, and although there are some reports in which ¹⁸F-fluorodeoxyglucose positron emission tomography (FDG‐PET) results are positive, the FDG uptakes vary and the imaging findings are very similar to those of lung cancer or malignant lymphoma. We present a case of surgically resected multifocal NLH which was differently identified by chest computed (CT) tomography appearance and FDG‐PET findings.

Thoracic surgery - FDG‐PET - nodular lymphoid hyperplasia

References

• 1 Travis W D, Galvin J R. Non-neoplastic pulmonary lymphoid lesions.  Thorax. 2001;  56 964-971
• 2 Abbondanzo S L, Rush W, Bijwaard K E et al. Nodular lymphoid hyperplasia of the lung: a clinicopathilogic study of 14 cases.  Am J Surg Pathol. 2000;  24 587-597
• 3 Kajiwara S, Sakai S, Soeda H et al. Multifocal nodular lymphoid hyperplasia of the lung.  J Thorac Imaging. 2005;  20 239-241
• 4 Sakurai H, Hada M, Oyama T. Nodular lymphoid hyperplasia of the lung: a very rare disease entity.  Ann Thorac Surg. 2007;  83 2197-2199
• 5 Shreve P D. Pseudolymphoma of the lung: benign pulmonary nodule with elevated fluorodeoxyglucose uptake.  Clin Nucl Med. 2000;  25 154-155
• 6 Kawahara K, Shiraishi T, Okabayashi K et al. Nodular lymphoid hyperplasia in the lung.  Thorac Cardiovasc Surg. 1996;  44 210-212