Exp Clin Endocrinol Diabetes 2008; 116(6): 363-365
DOI: 10.1055/s-2008-1042402
Case Report

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Primary Adrenal Lymphoma Presenting as Addison's Disease. Case Report and Review of the Literature

M. Kita 1 , E. Mandala 2 , A. Saratzis 1 , L. Ventzi 1 , I. Venizelos 3 , P. Keryttopoulos 2 , Z. Efstathiadou 1 , A. Garyfallos 2 , A. Avramides 1
  • 1Department of Endocrinology, Hippocratic General Hospital, Thessaloniki, Greece
  • 2D' Department of Internal Medicine, Aristotle University of Thessaloniki Hippocratic General Hospital, Thessaloniki, Greece
  • 3Department of Pathology, Hippocratic General Hospital, Thessaloniki, Greece
Further Information

Publication History

received 27.09.2007 first decision 26.10.2007

accepted 20.12.2007

Publication Date:
25 March 2008 (online)

Abstract

Primary Adrenal Lymphoma (PAL) is a very rare clinical entity. Adrenal insufficiency is a common complication of this pathology. Most patients present with clinical and laboratory findings of adrenal insufficiency and bilateral enlargement of the adrenal glands. We present a 78 year old woman admitted to our institution with typical clinical and laboratory findings of adrenal insufficiency. Computerized tomography (CT) of the abdomen revealed bilateral enlargement of the adrenal glands. The patient was eventually diagnosed with a diffuse large B-cell lymphoma after a CT-guided needle adrenal biopsy and treated with combined immuno-chemotherapy (R-LPD-COP). Twenty months after the initial evaluation, she is in good condition, with no signs of adrenal insufficiency.

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Correspondence

Dr. M. KitaMD 

Department of Endocrinology

Hippocration General Hospital

Konstantinoupoleos 49

Thessaloniki

54642 Greece

Email: a_saratzis@yahoo.gr

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