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Journal of Pediatric Neuroradiology 2013; 02(01): 017-032
DOI: 10.3233/PNR-13044
Review Article
Georg Thieme Verlag KG Stuttgart – New York

Premature white matter disease

Beth M. Kline-Fath
a   Departments of Radiology and Pediatrics, Cincinnati Children’s Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH, USA
,
Jean Tkach
a   Departments of Radiology and Pediatrics, Cincinnati Children’s Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH, USA
,
Stephanie Merhar
b   Divisions of Neonatology and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH, USA
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Publikationsverlauf

08. Februar 2012

26. März 2012

Publikationsdatum:
29. Juli 2015 (online)

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Abstract

Understanding the pathophysiology, imaging and correlative preterm outcome of white matter ischemic injury is important to improve neonatal clinical practices and to support preventative therapies. This article will focus on these topics in an attempt to provide greater understanding of premature white matter disease in this fragile age group.

Keywords

Prematurity - oligodendrocytes - magnetic resonance imaging - diffusion tensor imaging - magnetic resonance spectroscopy