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Journal of Pediatric Neuroradiology 2013; 02(03): 203-235
DOI: 10.3233/PNR-13070
Review Article
Georg Thieme Verlag KG Stuttgart – New York

Intracranial arterial aneurysms in children and young adults

Todd A. Abruzzo
a   Department of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA
b   Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA
d   Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA
e   Mayfield Clinic, Cincinnati, OH, USA
,
Vincent DiNapoli
a   Department of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA
,
Ralph Rahme
a   Department of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA
,
Biraj Patel
b   Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA
,
Kevin O’Brien
b   Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA
d   Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA
,
Lincoln Jimenez
a   Department of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA
b   Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA
,
Ravishankar Shivashankar
a   Department of Neurosurgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA
b   Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA
,
James L. Leach
b   Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA
d   Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA
,
John J. Bissler
c   Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA
,
Blaise Jones
b   Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA
d   Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA
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12. Dezember 2012

06. April 2013

Publikationsdatum:
29. Juli 2015 (online)

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Abstract

Intracranial arterial aneurysms are an important cause of hemorrhagic stroke during the first two decades of life. In the pediatric population, intracranial arterial aneurysms have a diverse etiological spectrum. The clinical course, response to treatment and long-term prognosis correlate strongly with the mechanism of lesion pathogenesis. A variety of phenotypes have been characterized, having variably overlapping features and differentiated according to the mechanism of pathogenesis: (1) idiopathic, (2) traumatic, (3) infectious, (4) flow related, (5) oncotic, (6) non-infectious inflammatory, (7) arteriopathic and (8) familial. The purpose of this report is to review intracranial aneurysmal disease in the pediatric population. We discuss contemporary approaches to diagnostic evaluation and clinical management, emphasizing interventional strategies and recent advances.

Keywords

Intracranial aneurysm - cerebral arterial diseases - arteriopathy - children