Impact of Stimulus Polarity on oVEMP Response Using the Belly-Tendon Electrode Montage
24. Oktober 2018
07. Dezember 2018
26. Mai 2020 (online)
One stimulus parameter not well established with respect to the ocular vestibular evoked myogenic potential (oVEMP) is stimulus polarity. Many research studies traditionally record oVEMPs using alternating polarity primarily.
The purpose of this study was to evaluate the effects of stimulus polarity on the oVEMP response under three different conditions (condensation, rarefaction, and alternating) with updated but established recording procedures—the belly-tendon electrode montage.
oVEMPs were assessed with changes in stimulus polarity in the seated upright position.
Thirty otologically normal participants (60 ears) with no history of hearing or balance disorders and normal middle ear function.
Data Collection and Analysis:
Five hundred–hertz air-conducted tone bursts at 95-dB nHL were used to evoke the oVEMP response while recordings were made from the contralateral eye to acoustical stimulation using the belly-tendon electrode montage. Measurements were made using three polarities: alternating, condensation, and rarefaction. Natus Bio-logic AEP hardware and software was used for all data collection and analysis.
Condensation stimulus phase provided the largest response amplitude compared with alternating and/or rarefaction. Rarefaction provided the earliest latency among stimulus polarities.
Condensation is a more effective stimulus polarity regarding response amplitude when recording the oVEMP. This study further supports the use of the belly-tendon electrode montage for recording the oVEMP response.
Key Wordselectrode montage - latency - N10 amplitude - otolith - phase-locking - response amplitude - stimulus polarity - utricle - vestibular evoked myogenic potential
Presented in part as a research poster at the American Balance Society Meeting, Scottsdale, AZ, February 28, 2017.
- Amorim FEAC, Sahdo AM, Giuliano LMP, Pinheiro DS, de Oliveira Braga NI, Manzano GM. 2017; Effects of the stimulus phase on the air-conducted ocular vestibular evoked myogenic potential in healthy subjects. Clin Neurophysiol 128: 262-269
- Bath A, Harris N, McEwan J, Yardley M. 1999; Effect of conductive hearing loss on the vestibulo‐collic reflex. Clin Otolaryngol 24: 181-183
- Cheng Y-L, Wu H-J, Lee G-S. 2012; Effects of plateau time and ramp time on ocular vestibular evoked myogenic potentials. J Vestib Res 22: 33-39
- Chihara Y, Iwasaki S, Ushio M, Murofushi T. 2007; Vestibular-evoked extraocular potentials by air-conducted sound: another clinical test for vestibular function. Clin Neurophysiol 118: 2745-2751
- Colebatch J, Halmagyi G. 1992; Vestibular evoked potentials in human neck muscles before and after unilateral vestibular deafferentation. Neurology 42: 1635
- Colebatch J, Halmagyi G, Skuse N. 1994; Myogenic potentials generated by a click-evoked vestibulocollic reflex. J Neurol Neurosurg Psychiatry 57: 190-197
- Curthoys IS. 2010; A critical review of the neurophysiological evidence underlying clinical vestibular testing using sound, vibration and galvanic stimuli. Clin Neurophysiol 121: 132-144
- Curthoys IS. 2017; The new vestibular stimuli: sound and vibration—anatomical, physiological and clinical evidence. Exp Brain Res 235 (04) 957-972
- Curthoys I, Grant J. 2015; How does high-frequency sound or vibration activate vestibular receptors?. Exp Brain Res 233: 691-699
- Curthoys IS, Halmagyi GM. 1995; Vestibular compensation: A review of the oculomotor, neural, and clinical consequences of unilateral vestibular loss. J Vestib Res 5 (02) 67-107
- Curthoys IS, Iwasaki S, Chihara Y, Ushio M, McGarvie LA, Burgess AM. 2011; The ocular vestibular-evoked myogenic potential to air-conducted sound; probable superior vestibular nerve origin. Clin Neurophysiol 122: 611-616
- Curthoys IS, MacDougall HG, Vidal P-P, De Waele C. 2017; Sustained and transient vestibular systems: a physiological basis for interpreting vestibular function. Front Neurol 8: 117
- Govender S, Cheng PY, Dennis DL, Colebatch JG. 2016; a Electrode montage and gaze effects on ocular vestibular evoked myogenic potentials (oVEMPs). Clin Neurophysiol 127: 2846-2854
- Govender S, Rosengren SM, Colebatch JG. 2011; Vestibular neuritis has selective effects on air-and bone-conducted cervical and ocular vestibular evoked myogenic potentials. Clin Neurophysiol 122: 1246-1255
- Govender S, Rosengren SM, Dennis DL, Lim LJ, Colebatch JG. 2016; b Contrasting phase effects on vestibular evoked myogenic potentials (VEMPs) produced by air-and bone-conducted stimuli. Exp Brain Res 234: 141-149
- Halmagyi G, Curthoys I. 2000. Otolith function tests. In: Herdman SJ. Vestibular Rehabilitation. Philadelphia, PA: F.A. Davis; 196-214
- Iwasaki S, Smulders Y, Burgess A, McGarvie L, Macdougall H, Halmagyi G, Curthoys I. 2008; Ocular vestibular evoked myogenic potentials to bone conducted vibration of the midline forehead at Fz in healthy subjects. Clin Neurophysiol 119: 2135-2147
- Leigh R, Zee D. 2006. The Neurology of Eye Movements, Edition 4 (Contemporary Neurology Series). New York, NY: Oxford University Press;
- Lempert T, Gianna C, Brookes G, Bronstein A, Gresty M. 1998; Horizontal otolith-ocular responses in humans after unilateral vestibular deafferentation. Exp Brain Res 118 (04) 533-540
- Leyssens L, Heinze B, Vinck B, Van Ombergen A, Vanspauwen R, Wuyts FL, Maes LK. 2017; ‘Standard’ versus ‘nose reference’ electrode placement for measuring oVEMPs with air-conducted sound: test–retest reliability and preliminary patient results. Clin Neurophysiol 128: 312-322
- Lim LJ, Dennis DL, Govender S, Colebatch JG. 2013; Differential effects of duration for ocular and cervical vestibular evoked myogenic potentials evoked by air- and bone-conducted stimuli. Exp Brain Res 224: 437-445
- Makowiec K, McCaslin DL, Jacobson GP, Hatton K, Lee J. 2017; Effect of electrode montage and head position on air-conducted ocular vestibular evoked myogenic potential. Am J Audiol 26 (02) 180-188
- McCaslin DL, Jacobson GP, Harry T. 2008; The recordability of two sonomotor responses in young normal subjects. J Am Acad Audiol 19: 542-547
- McCue M, Guinan J. 1994; Acoustically responsive fibers in the vestibular nerve of the cat. J Neurosci 14: 6058-6070
- Murnane OD, Akin FW, Kelly JK, Byrd S. 2011; Effects of stimulus and recording parameters on the air conduction ocular vestibular evoked myogenic potential. J Am Acad Audiol 22: 469-480
- Piker EG, Jacobson GP, McCaslin DL, Hood LJ. 2011; Normal characteristics of the ocular vestibular evoked myogenic potential. J Am Acad Audiol 22: 222-230
- Rosengren S, Todd NM, Colebatch J. 2005; Vestibular-evoked extraocular potentials produced by stimulation with bone-conducted sound. Clin Neurophysiol 116: 1938-1948
- Sandhu JS, George SR, Rea PA. 2013; The effect of electrode positioning on the ocular vestibular evoked myogenic potential to air-conducted sound. Clin Neurophysiol 124: 1232-1236
- Todd NP, Rosengren SM, Colebatch JG. 2009; A utricular origin of frequency tuning to low-frequency vibration in the human vestibular system?. Neurosci Lett 451: 175-180
- Todd NPM, Rosengren SM, Aw ST, Colebatch JG. 2007; Ocular vestibular evoked myogenic potentials (OVEMPs) produced by air-and bone-conducted sound. Clin Neurophysiol 118: 381-390
- Todd NPM, Rosengren SM, Colebatch JG. 2008; A source analysis of short-latency vestibular evoked potentials produced by air-and bone-conducted sound. Clin Neurophysiol 119: 1881-1894
- Weber KP, Rosengren SM, Michels R, Sturm V, Straumann D, Landau K. 2012; Single motor unit activity in human extraocular muscles during the vestibulo‐ocular reflex. J Physiol 590: 3091-3101
- Xue J, Peterson EH. 2006; Hair bundle heights in the utricle: differences between macular locations and hair cell types. J Neurophysiol 95: 171-186