Endoscopic Ultrasound‑guided Confirmation of Malignancy Arising from Fistula‑in‑ano

ABSTRACT

Adenocarcinoma arising from a chronic anorectal fistula (ARF) is rare, and there are no more than 200 cases in literature. We report a case of endoscopic ultrasound‑guided biopsy‑proven adenocarcinoma arising from long‑standing ARF.

Keywords

Adenocarcinoma - anorectal fistula - endoscopic ultrasound

• REFERENCES

• 1 Abcarian H. Anorectal infection: Abscess-fistula. Clin Colon Rectal Surg 2011; 24: 14-21
• 2 Whiteford MH, Kilkenny 3rd J, Hyman N, Buie WD, Cohen J, Orsay C. et al. Practice parameters for the treatment of perianal abscess and fistula-in-ano (revised). Dis Colon Rectum 2005; 48: 1337-42
• 3 Ramanujam PS, Prasad ML, Abcarian H, Tan AB. Perianal abscesses and fistulas. A study of 1023 patients. Dis Colon Rectum 1984; 27: 593-7
• 4 Cirocco WC, Reilly JC. Challenging the predictive accuracy of Goodsall's rule for anal fistulas. Dis Colon Rectum 1992; 35: 537-42
• 5 Nazki S, Chowdari NA, Parray FQ, Wani RA, Samad LA. Adenocarcinoma arising from fistula in ano. J Gastrointest Dig Syst 2015; 5: 370
• 6 Maejima T, Kono T, Orii F, Maemoto A, Furukawa S, Liming W. et al. Anal canal adenocarcinoma in a patient with longstanding Crohn's disease arising from rectal mucosa that migrated from a previously treated rectovaginal fistula. Am J Case Rep 2016; 17: 448-53
• 7 Iesalnieks I, Gaertner WB, Glass H, Strauch U, Hipp M, Agha A. et al. Fistula-associated anal adenocarcinoma in Crohn's disease. Inflamm Bowel Dis 2010; 16: 1643-8
• 8 Dukes CE, Galvin C. Colloid carcinoma arising within fistulae in the anorectal region. Ann R Coll Surg Engl 1956; 18: 246-61
• 9 Rossner C. Relation of fistula-in-ano to cancer of the anal canal. Trans Am Proctol Soc 1934; 35: 65-70
• 10 Purkayastha A, Sharma N, Dutta V, Bisht N, Pandya T. Mucinous adenocarcinoma of perianal region: An uncommon disease treated with neo-adjuvant chemo-radiation. Transl Gastroenterol Hepatol 2016; 1: 52