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Int Arch Otorhinolaryngol 2013; 17(03): 340-343
DOI: 10.7162/S1809-977720130003000015
Review Article
Thieme Publicações Ltda Rio de Janeiro, Brazil

Middle ear adenoma with neuroendocrine differentiation: relate of two cases and literature review

Aline Gomes Bittencourt
1   Otolaryngologist, Ph.D. Student. Department of Otolaryngology, University of São Paulo School of Medicine, São Paulo, Brazil.
,
Robinson Koji Tsuji
2   M.D., Ph.D. - Associated Doctor. Department of Otolaryngology, University of São Paulo School of Medicine, São Paulo, Brazil.
,
Francisco Cabral Junior
3   M.D., Otolaryngology Resident. Department of Otolaryngology, University of São Paulo School of Medicine, São Paulo, Brazil.
,
Larissa Vilela Pereira
3   M.D., Otolaryngology Resident. Department of Otolaryngology, University of São Paulo School of Medicine, São Paulo, Brazil.
,
Anna Carolina de Oliveira Fonseca
1   Otolaryngologist, Ph.D. Student. Department of Otolaryngology, University of São Paulo School of Medicine, São Paulo, Brazil.
,
Venâncio Alves
4   M.D. Ph.D. Professor and Chairman - Department of Patology, University of São Paulo School of Medicine, São Paulo, Brazil.
,
Ricardo Ferreira Bento
5   M.D. Ph.D. Professor and Chairman - Department of Otolaryngology, University of São Paulo School of Medicine, São Paulo, Brazil.
› Author Affiliations
Further Information

Publication History

20 December 2012

18 February 2013

Publication Date:
21 January 2014 (online)

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Summary

Introduction: Adenomas with neuroendocrine differentiation are defined as neuroendocrine neoplasms, and they are rarely found in the head and neck.

Objective: To describe two cases of a middle ear adenoma with neuroendocrine differentiation, with a literature review.

Case Report: Patient 1 was a 41-year-old woman who presented with a 3-year history of left aural fullness associated with ipsilateral “hammer beating” tinnitus. Patient 2 was a 41-year-old male who presented with unilateral conductive hearing loss.

Conclusion: Adenoma with neuroendocrine differentiation of the middle ear is a rare entity, but it should be considered in patients with tinnitus, aural fullness, and a retrotympanic mass and remembered as a diferential diagnosis of tympanic paraganglioma.

Keywords

Neuroendocrine Tumors - Hearing Loss - Adenoma
 

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