31. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber

Abstracts (HTML) List of Authors

Maasoumy, B

Kinetic of Hepatitis B core-related antigen (HBcrAg) levels in chronic hepatitis B during NUC therapy
Interruption of nucleos(t)ide analogue therapy in HBeAg negative chronic hepatitis B – A new concept to achieve HBsAg decline?
Clinical significance of drug-drug interactions during HCV therapy with sofosbuvir and simeprevir in comparison to first wave protease inhibitors
Eligibility and safety of sofosbuvir in a real-world single center cohort of patients with advanced cirrhosis, including decompensated cirrhosis

Maass, T

Smad7 suppresses HCC development in a DEN induced mouse model

Macheleidt, I

The pluripotency involved factors, Lin28 and Notch1 are targets of neuronal miRNAs in hepatic stellate cells

Mahli, A

Identification of cytochrome CYP2E1 as critical mediator of alcohol effects on steatotic hepatocytes
ERK and p38 activation are central mediators of irinotecan-induced steatohepatitis

Mai, M

A common polymorphism of tumor necrosis factor receptor-associated factor 6 (TRAF6) is associated with an increased risk for spontaneous bacterial peritonitis

Mais, C

Endocytosis of the signal transducing receptor gp130 as mechanism to fine-tune IL-6 responses

Malinowski, M

Volumen-Funktionsplanung in der Leberchirurgie: Was kann man von der Kombination aus 3D- CT- Volumetrie mit dem LiMAx-Test erwarten?
Risikofaktoren für metabolische Störungen nach Lebertransplantation: Analyse von Daten nüchterner Patienten

Mandorfer, M

Zusammenhang der zirkulierenden miRNA-122 Spiegel mit der portalen Hypertension bei HIV/HCV-positiven Patienten

Manka, P

Upregulation of Krüppel-Like Factor 6 is associated with acute liver injury in mice and humans
Higher thyroid hormone levels are associated with better outcome in acute liver failure

Mann, A

Bcl-3 reguliert die hepatische Lipo- und Gluconeogenese in einem murinen, hochkalorischen Fütterungsmodell der nicht-alkoholischen Fettlebererkrankung (NAFLD)

Manns, M

Histopathology of chronic Hepatitis E
Increased serum levels of regenerative miRNAs in patients with spontaneous recovery from acute liver failure

Manns, MP

Virotherapy overcomes tumor resistance to PD-1-immunotherapy by broad mutanome-directed T cell responses in mice
Kinetic of Hepatitis B core-related antigen (HBcrAg) levels in chronic hepatitis B during NUC therapy
Impact of genetic polymorphisms in the SCARB1 gene on hepatitis C virus
Large scale biomarker profiling reveals distinct cytokine and chemokine signatures distinguishing different acute and chronic hepatitis virus infections
Oxidiertes Low Density Lipoprotein (oxLDL) – endogener HCV Eintritt Inhibitor und Prädiktor für SVR nach Interferon-basierter Therapie bei chronischer Hepatitis C
Modulation of HCV reinfection by fibroblast growth factor-2 and other non-interferon mediators
Serum biomarker profile can predict the outcome of acute HCV infection
Broad and cross-genotype-specific T cell responses during acute hepatitis E virus infection
Biomarkers to predict the clinical outcome of hepatitis delta
Clinical significance of drug-drug interactions during HCV therapy with sofosbuvir and simeprevir in comparison to first wave protease inhibitors
Delayed early HCV RNA response during IFN-free therapy with sofosbuvir in interferon-ineligible patients with advanced cirrhosis
Early on-treatment HDV-RNA kinetics are not predictive for long-term response to a PEG-IFNa therapy of hepatitis delta
Human adult liver stem cells generated from patient samples
The differential phenotype and functionality of CMV- and EBV-specific CD8 T cells in patients with chronic hepatitis C is associated with an altered plasma cytokine milieu
Eligibility and safety of sofosbuvir in a real-world single center cohort of patients with advanced cirrhosis, including decompensated cirrhosis
p53/telomerase-dependent oncolytic adenoviruses harboring a p53-dependent feed forward loop results in reduced viral liver burden

Manowsky, J

Impairment of insulin signaling in hepatocytes by supernatants of insulin-activated macrophages

Marbach, E

Neue Aspekte der Regulation des Lipidmetabolismus während der Entstehung von NAFDL

Marhenke, S

Role of RAGE and its ligands S100A8/A9 in hepatocellular carcinoma onset and development

Markova, AA

Interruption of nucleos(t)ide analogue therapy in HBeAg negative chronic hepatitis B – A new concept to achieve HBsAg decline?

Marquardt, J

Cooperative function of YAP and TAZ in hepatocytes and hepatocarcinogenesis
Array-based gene expression analysis of M1/M2-polarized macrophages during treatment with multi-kinase inhibitor Sorafenib
Einfluss metabolischer Faktoren auf die Prognose von Patienten mit fortgeschrittenem hepatozellulärem Karzinom unter Sorafenib Therapie
Gene signatures define chromosomal instability (CIN) and poor survival in HCC patients
Identification of potential driver genes involved in chromosomal instability and tumor cell migration in hepatocarcinogenesis
Relevance of organic cation transporter OCT1 (SLC22A1) in Diethylnitrosamine-initiated and Phenobarbital-promoted hepatocellular carcinoma in OCT3- knockout mice

Marquardt, JU

The hepatic tumor microenvironment is important for the CSC phenotype and progression of liver cancer

Martin, C

Liver inflammation abrogates T cell mediated tolerance against particulate antigens induced by liver Kupffer cells

Martin, IV

Comparative analysis of C5aR and C5L2 receptor deficiency in liver and kidney fibrosis

Martin, M

Tumor infiltrating IL-33 producing effector-memory CD8+ T cells in resected hepatocellular carcinoma prolong patient survival

Masing, N

Rolle des Mas Rezeptors in der Leberfibrose

Mastrobuoni, G

Application of mathematical modelling to assess the functional importance of HIF1A for hepatoma biology

Mathé, Z

All-In-One: Advanced human parenchymal and non-parenchymal liver cell preparation

Matusch, A

Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) in trace metal imaging of experimental and clinical metal disorders

Matz-Soja, M

A new modelling approach for Gli transcription factor network in hepatocytes
A quantitative metabolomic profiling and corresponding modeling approach of hepatocytes with activated Wnt/ß-Catenin signaling
Cooperation of Hedgehog and Wnt/β-Catenin signalling in regulation of steroidogenesis in the liver
Neue Aspekte der Regulation des Lipidmetabolismus während der Entstehung von NAFDL
Regulation of energy metabolism in hepatocytes with induced steatosis

Megger, DA

Proteasome subunit alpha type-6 regulates the expression of proviral host genes in hepatitis C virus infection

Mehrabi, A

Methylome screen identifies epigenetically deregulated microRNAs in cholangiocarcinoma

Meindl-Beinker, N

Targeting TGF-β2 in chronic liver diseases

Meindl-Beinker, NM

Smad7 suppresses HCC development in a DEN induced mouse model

Meissner, EG

Increased Lysyl oxidase-like 2 (LOXL2) gene expression accurately designates advanced liver fibrosis induced by the Hepatitis C Virus (HCV) regardless race, blood specimen or co-infection with the Human Immunodeficiency Virus (HIV)

Melter, M

Reduced HNF3b (FOXA2) levels in steatosis leads to diminished expression of anti-lipoapoptotic protein ALR
Hepatic detoxification and anti-oxidative response in liver tissue with cholestasis: analysis of Nrf2 dependent gene expression

Merle, U

Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) in trace metal imaging of experimental and clinical metal disorders

Meurer, SK

Platelet-derived growth factor-D intensifies fibrogenesis through upregulation of TIMP-1 expression and signalling through both platelet-derived growth factor receptors type α and β

Meyer, AS

Loss of cell polarity defines a cancer-prone phenotype in liver epithelial cells

Meyer, ASK

Identification of potential driver genes involved in chromosomal instability and tumor cell migration in hepatocarcinogenesis

Meyer, HE

Proteasome subunit alpha type-6 regulates the expression of proviral host genes in hepatitis C virus infection

Michael, MP

Interruption of nucleos(t)ide analogue therapy in HBeAg negative chronic hepatitis B – A new concept to achieve HBsAg decline?

Michler, T

Clinical immune monitoring: Impact of in vitro PBMC expansion on quantity and quality of HBV-specific CD4 and CD8 T cells

Milkiewicz, P

Serum sterol levels indicate distorted cholesterol homeostasis in cirrhotic patients with primary biliary cirrhosis

Missing, L

Inhibition of the transcriptional regulation of CDCA-induced BSEP expression by IL-1β involves the IL-1β triggered activation of autocrine chemokine circuits

Mix, C

Delayed early HCV RNA response during IFN-free therapy with sofosbuvir in interferon-ineligible patients with advanced cirrhosis

Moeller, LC

Higher thyroid hormone levels are associated with better outcome in acute liver failure

Mogler, C

Primary hepatic malignant epitheloid Hemangioendothelioma represent a genetically homogenous tumor entity

Mohs, A

Pharmakologische oder genetische Intervention des CCL5/RANTES Signalweges im in vivo Modell einer chronischer Leberentzündung vermindert die Fibrogenese und Progression zum Hepatozellulären Karzinom

Moldenhauer, G

Bispecific antibody constructs mediate immunotherapeutic retargeting of effector cells towards HBV infected target cells

Momburg, F

Bispecific antibody constructs mediate immunotherapeutic retargeting of effector cells towards HBV infected target cells

Moriconi, F

HMGB1 inflammosome activity modulates HIF-1α in a rat model of thioacetamide (TAA)-induced chronic liver damage and cholangiocarcinoma development

Moro, N

Inactivation of Cyclin E1 acts pro-apoptotic and anti-proliferative in primary hepatoma cells and protects from hepatocarcinogenesis in mice

Morton, CH

Cholestasis and bile acids induce expression of the oncofetal marker Nope in adult murine hepatocytes independent of Fxr

Müller, J

Indirekte Wechselwirkungen zwischen HCC (Hep3B) und humanen mesenchymalen Stammzellen in vitro und in vivo

Müller, M

Identification of cytochrome CYP2E1 as critical mediator of alcohol effects on steatotic hepatocytes
ERK and p38 activation are central mediators of irinotecan-induced steatohepatitis
Functional effects of monocarboxylate transporter 1 expression in activated hepatic stellate cells

Müller-Newen, G

Inactivation of Cyclin E1 acts pro-apoptotic and anti-proliferative in primary hepatoma cells and protects from hepatocarcinogenesis in mice

Muñoz Álvarez, KA

Development of delivery, targeting, and imaging strategies to improve oncolytic vesicular stomatitis virus therapy for hepatocellular carcinoma

Münst, B

In vitro generation of 3-dimensional organoid liver structures using differentiatedhuman cells

Münzberg, C

Aldosterone stimulates the non-genomic signaling pathway of the mineralocorticoid receptor in hepatic stellate cells