Treating hot flushes in menopausal women with homeopathic treatment–Results of an observational study

Abstract

Objective: There is great controversy concerning treatment for menopausal symptoms. We evaluated homeopathic treatments for hot flushes and their effect on quality of life in menopausal women.

Methods: Open, multi-national prospective, pragmatic and non-comparative observational study of homeopathic treatments prescribed and their effectiveness, observing their impact on quality of life.

Results: Ninety-nine physicians in 8 countries took part in this study and included 438 patients with an average age of 55.

Homeopathic medicines were prescribed to all patients; 98% of the prescription lines were for homeopathic medicines. Lachesis mutus, Belladonna, Sepia officinalis, Sulphur and Sanguinaria canadensis were the most prescribed. A non-homeopathic treatment and/or food supplement prescribed for 5% of the patients.

This observational study revealed a significant reduction (p<0.001) in the frequency of hot flushes by day and night and a significant reduction in the daily discomfort they caused (mean fall of 3.6 and 3.8 points respectively, on a 10 cm visual analogue scale; p<0.001).

Ninety percent of the women reported disappearance or lessening of their symptoms, these changes mostly taking place within 15 days of starting homeopathic treatment.

Conclusions: The results of this observational study suggest that homeopathic treatment for hot flushes in menopausal women is effective. Further studies including randomized controlled trials should be conducted.

Keywords

homeopathy - hot flushes - homeopathic treatment - observational study - menopause

• References

• 1 Boekhout A.H., Beijnen J.H., Schellens J.H. Symptoms and treatment in cancer therapy-induced early menopause. Oncologist 2006; 11 (06) 641-654.
• 2 Philp H.A. Hot flashes–a review of the literature on alternative and complementary treatment approaches. Altern Med Rev 2003; 8 (03) 284-302.
• 3 Afssaps/Anaes. Rapport d’orientation. Traitements hormonaux substitutifs de la ménopause. 11 mai 2004, p. 78.
• 4 Jouanny J, Crapanne JB, Dancer H, Masson JL. La ménopause. Thérapeutique homéopathique, Possibilités en pathologie chronique. Editions Boiron, 2000, pp. 276–288 (chapter 10).
• 5 Jacobs J., Herman P., Heron K. et al. Homeopathy for menopausal symptoms in breast cancer survivors: a preliminary randomized controlled study. J Altern Complement Med 2005; 11 (01) 21-27.
• 6 Thompson E.A., Reilly D. The homeopathic approach to the treatment of symptoms of oestrogen withdrawal in breast cancer patients. A prospective observational study. Homeopathy 2003; 92 (03) 131-134.
• 7 Thompson E.A., Montgomery A., Douglas D. et al. A pilot, randomized, double-blinded, placebo-controlled study of individualized homeopathy for symptoms of estrogen withdrawal in breast-cancer survivors. J Altern Complement Med 2005; 11 (01) 13-20.
• 8 Kronenberg F., Fugh-Berman A. Complementary and alternative medicine for menopausal symptoms: a review of randomized, controlled studies. Ann Intern Med 2002; 137 (10) 805-813.
• 9 Relton C., Weatherley-Jones E. Homeopathy service in a National Health Service community menopause clinic: audit of clinical outcomes. J Br Menopause Soc 2005; 11 (02) 72-73.
• 10 Thompson E.A. Homeopathy and the menopause. J Br Menopause Soc 2002; 8 (04) 151-154.
• 11 Carroll D.G. Nonhormonal therapies for hot flashes in menopause. Am Fam Physician 2006; 73 (03) 457-464.
• 12 Clover A., Ratsey D. Homeopathic treatment of hot flushes: a pilot study. Homeopathy 2002; 91 (02) 75-79.
• 13 Rossouw J.E., Anderson G.L., Prentice R.L. et al. Writing group for the Women's Health Initiative investigators. Risks and benefits of estrogen plus progestin in healthy post menopausal women. Principal results from the Women's Health Initiative randomized controlled Study. JAMA 2002; 288: 321-333.
• 14 Cauley J.A., Robbins J., Chen Z. et al. Women's Health Initiative Investigators. Effects of estrogen plus progestin on risk of fracture and bone mineral density: the Women's Health Initiative randomized study. JAMA 2003; 290 (13) 1729-1738.
• 15 Chlebowski R.T., Hendrix S.L., Langer R.D. et al. WHI Investigators. Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized Study. JAMA 2003; 289 (24) 3243-3253.
• 16 Anderson G.L., Judd H.L., Kaunitz A.M. et al. Women's Health Initiative Investigators. Effects of estrogen plus progestin on gynecologic cancers and associated diagnostic procedures: the Women's Health Initiative randomized study. JAMA 2003; 290 (13) 1739-1748.
• 17 Manson J.E., Hsia J., Johnson K.C. et al. Women's Health Initiative Investigators. Estrogen plus progestin and the risk of coronary heart disease. N Engl J Med 2003; 349: 523-534.
• 18 Shumaker S.A., Legault C., Rapp S.R. et al. WHIMS Investigators. Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled study. JAMA 2003; 289 (20) 2651-2662.
• 19 Hays J., Ockene J.K., Brunner R.L. et al. Women's Health Initiative Investigators. Effects of estrogen plus progestin on health-related quality of life. N Engl J Med 2003; 348: 1839-1854.
• 20 Wassertheil-Smoller S., Hendrix S.L., Limacher M. et al. WHI Investigators. Effect of estrogen plus progestin on stroke in postmenopausal women: the Women's Health Initiative: a randomized study. JAMA 2003; 289 (20) 2673-2684.
• 21 Li C.I., Malone K.E., Porter P.L. et al. Relationship between long durations and different regimens of hormone therapy and risk of breast cancer. JAMA 2003; 289 (24) 3254-3263.
• 22 Beral V. Million Women Study Collaborators, Breast cancer, hormone-replacement therapy in the Million Women Study (MWS). Lancet 2003; 362: 419-427.
• 23 Afssaps. Mise au point actualisée sur le traitement hormonal substitutif de la ménopause (THS). Décembre 2003, 5p.
• 24 Afssaps. Mise au point. Le traitement hormonal de la ménopause (THM). Juin 2006, pp. 21.