Lobke Desomer et al. The clinical significance and synchronous polyp burden of large
(≥ 20 mm) sessile serrated polyps in patients without serrated polyposis syndrome
Patients with at least two sessile serrated polyps (SSPs) at least one of which was
≥ 20 mm, and who did not fulfill the WHO criteria for serrated polyposis syndrome,
have similar rates of personal and family history of colorectal cancer, and a similar
synchronous polyp burden as patients with serrated polyposis syndrome. Of note, the
risk in those with a solitary large SPS is lower. Serrated polyposis syndrome is under-recognized,
warranting a renewed focus on the education of endoscopists by international endoscopy
societies.
