Gastric outlet obstruction (GOO) reduces quality of life and compromises nutrition.
Duodenal stenting is the first-line treatment but does not completely relieve symptoms.
Surgical gastrojejunostomy improves the quality of life in patients who are expected
to survive for a long time. In patients with benign conditions such as chronic pancreatitis,
duodenal stents are ineffective (being associated with high migration rates), and
surgical gastrojejunostomy is both difficult and risky because of the significant
malnutrition and frequent portal hypertension attributable to portosplenic thromboses.
Recently, endoscopic ultrasound (EUS)-guided gastrojejunostomy using electrocautery
to place a lumen-apposing metal stent has emerged as a new minimally invasive procedure.
Three techniques have been reported [1]: the single-balloon-occluded technique [2], double-balloon-occluded gastrojejunostomy bypass [3] (EPASS), and a direct technique [4]. The latter is the most attractive technique but is associated with the risk of
puncture of an empty jejunum. Here, we report a case treated via direct EUS-guided
gastrojejunostomy using a nasobiliary drain connected to a waterjet system.
A 55-year-old man with GOO secondary to chronic pancreatitis and portal vein thrombosis
was hospitalized in our gastroenterology unit ([Fig. 1]). Surgical gastrojejunostomy was contraindicated because of massive portal hypertension;
we thus performed EUS-guided gastrojejunostomy ([Video 1]).
Fig. 1 Gastric outlet obstruction due to chronic pancreatitis.
Video 1 Gastrojejunostomy using nasobiliary drain and lumen-apposing metal stent.
The first step featured dilation of the stenosis to allow a nasobiliary drain to be
placed in the jejunum ([Fig. 2]). The drain was connected to a waterjet system, which allowed continuous jejunal
filling with normal saline containing small amounts of a carmine coloring agent and
contrast ([Fig. 3]). A therapeutic echoendoscope was inserted into the stomach, parallel to the nasobiliary
drain. Constant filling of the jejunum by the waterjet facilitated clear visualization
of the dilated jejunum and performance of direct EUS-guided gastrojejunostomy using
a HOT AXIOS device (Boston Scientific, Marlborough, Massachusetts, USA) with diameter
of 20 mm ([Fig. 4], [Fig. 5], [Fig. 6]).
Fig. 2 Dilation of the duodenal stenosis.
Fig. 3 Filling of the jejunal loop with carmine-colored normal saline.
Fig. 4 Opening of the distal flange of the lumen-apposing metal stent.
Fig. 5 Endoscopic view of the gastrojejunostomy.
Fig. 6 Coronal computed tomography view of the gastrojejunostomy with contrast ingestion.
One day later, food was successfully taken, and the patient was discharged the next
day. Thus, the use of a nasobiliary drain connected to a waterjet system is a simple
way to facilitate direct EUS-guided gastrojejunostomy via constant filling of the
target jejunum.
Endoscopy_UCTN_Code_TTT_1AS_2AG
Endoscopy E-Videos is a free access online section, reporting on interesting cases and new techniques
in gastroenterological endoscopy. All papers include a high quality video and all
contributions are freely accessible online.
This section has its own submission website at https://mc.manuscriptcentral.com/e-videos
