Genderspezifische Aspekte in der endokrinen Chirurgie

Das biologische (z. B. Sexualhormone, Genexpression der X- und Y-Chromosomen) und soziokulturelle Geschlecht (z. B. Risikoverhalten, Lebenserfahrung) führen zu Geschlechterunterschieden auch in der endokrinen Chirurgie. Bis heute sind vor allem genderspezifische Unterschiede bezüglich Epidemiologie, Diagnose und Therapie bei kardiovaskulären, onkologischen und psychiatrischen Erkrankungen bekannt.

Publication History

Article published online:
04 June 2020

• Literatur

• 1 Rahbari R, Zhang L, Kebebew E. Thyroid cancer gender disparity. Future Oncol 2010; 6: 1771-1779
• 2 Xu S, Chen G, Peng W. et al. Oestrogen action on thyroid progenitor cells: relevant for the pathogenesis of thyroid nodules?. J Endocrinol 2013; 218: 125-133
• 3 Schumm-Dräger PM, Feldkamp J. Schilddrüsenkrankheiten in Deutschland. Präv Gesundheitsf 2007; 2: 153-158
• 4 Gan T, Randle RW. The role of surgery in autoimmune conditions of the thyroid. Surg Clin North Am 2019; 99: 633-648
• 5 Bartsch DK, Dotzenrath C, Vorländer C. et al. Current practice of surgery for benign goitre-An analysis of the prospective DGAV Studoq thyroid registry. J Clin Med 2019; DOI: 10.3390/jcm8040477.
• 6 Edafe O, Antakia R, Laskar N. et al. Systematic review and meta-analysis of predictors of post-thyroidectomy hypocalcaemia. Br J Surg 2014; 101: 307-320
• 7 Promberger R, Ott J, Kober F. et al. Risk factors for postoperative bleeding after thyroid surgery. Br J Surg 2012; 99: 373-379
• 8 Castellano E, Attanasio R, Boriano A. et al. Sex difference in the clinical presentation of primary hyperparathyroidism: Influence of menopausal status. J Clin Endocrinol Metab 2017; 102: 4148-4152
• 9 Vodopivec DM, Silva AM, Garcia-Banigan DC. et al. Gender difference in bone mineral density in patients with sporadic primary hyperparathyroidism. Endocrinol Diab Metab 2018; DOI: 10.1002/edm2.37.
• 10 Mazeh H, Sippel RS, Chen H. The role of gender in primary hyperparathyroidism: Same disease, different presentation. Ann Surg Oncol 2012; 19: 2958-2962
• 11 Mantero F, Terzolo M, Arnaldi G. et al. A survey on adrenal incidentaloma in Italy. J Clin Endocrinol Metab 2000; 85: 637-644
• 12 Ahn SH, Kim JH, Baek SH. et al. Characteristics of adrenal incidentalomas in a large, prospective computed tomography-based multicenter study: The COAR Study in Korea. Yonsei Med J 2018; 59: 501-510
• 13 Pecori Giraldi F, Moro M, Cavagnini F. Gender-related differences in the presentation and course of Cushingʼs disease. J Clin Endocrinol Metab 2003; 88: 1554-1558
• 14 Utsumi T, Kamiya N, Endo T. et al. Development of a nomogram to predict hypertension cure after laparoscopic adrenalectomy in patients with primary aldosteronism. World J Surg 2014; 38: 2640-2644
• 15 Lai EW, Perera SM, Havekes B. et al. Gender-related differences in the clinical presentation of malignant and benign pheochromocytoma. Endocrine 2008; 34: 96-100
• 16 Genus TSE, Bouvier C, Wong KF. et al. Impact of neuroendocrine morphology on cancer outcomes and stage at diagnosis: a UK nationwide cohort study 2013–2015. Br J Cancer 2019; 121: 966-972 doi:10.1038/s41416-019-0606-3
• 17 Goudet P, Bonithon-Kopp C, Ruszniewski P. et al. Gender-related differences in MEN1 lesion occurrence and diagnosis: a cohort study of 734 cases from the Groupe dʼetude des Tumeurs Endocrines. Eur J Endocrinol 2011; 165: 97-105
• 18 Hallet J, How Lim Law C, Cuiker M. et al. Exploring the rising incidence of neuroendocrine tumors: A population-based analysis of epidemiology, metastatic presentation, and outcomes. Cancer 2015; 121: 589-597
• 19 Karabukut K, Akyildiz HY, Lance C. et al. Multimodality treatment of neuroendocrine liver metastases. Surgery 2011; 150: 316-325