Erfahrungsheilkunde 2020; 69(04): 223-229
DOI: 10.1055/a-1205-8025
Praxis

Stärkung des Immunsystems durch Sport – Eine Frage der Intensität

Jens Freese
,
Sebastian Proschinger

Zusammenfassung

Sport und körperliche Aktivität haben nicht nur präventivmedizinische Bedeutung für die Gesundheit, sondern auch für die Leistungsfähigkeit des Immunsystems. Entscheidend ist die Dosis: Diabetiker profitierten in einer Studie von moderater Aktivität mit besserer kardiorespiratorischer Fitness, niedrigerem Körperfettanteil, niedrigerem LDL-Cholesterin und besserer Insulinsensitivität. Leistungssportler hingegen leiden auffällig häufig an Infekten der oberen Atemwege, gastrointestinalen Störungen und Erschöpfungssyndromen.

Die sportimmunologische Forschung ist in den letzten Jahrzehnten exponentiell gewachsen. Auf Basis des derzeitigen Wissens kann abgeleitet werden: Das Immunsystem lässt sich trainieren, mit der individuell angepassten Dosis. Die Immunoseneszenz ist durch tägliche Bewegung positiv beeinflussbar. Und immer deutlicher zeigt sich: Die Intensität ist ein entscheidender Faktor, um das Immunsystem zu stimulieren.

Abstract

From the point of view of preventive medicine, sport and physical activity are not only significant for health but also for the performance of the immune system. The decisive factor is the dose: In one study is was shown that diabetics benefited from moderate activity in the form of better cardiorespiratory fitness, lower body fat, lower LDL cholesterol, and better insulin sensitivity. Competitive athletes, on the other hand, remarkably often suffer from infections of the upper respiratory tract, gastrointestinal disorders, and fatigue syndromes.

Research in the field of sports immunology has increased exponentially in the last decades. Based on current knowledge, the following can be deduced: The immune system can be trained with the individually adjusted dose. The immunosenescence can be positively influenced by daily exercise. And it is becoming increasingly clear: The intensity is a decisive factor in stimulating the immune system.



Publication History

Article published online:
12 August 2020

© MVS Medizinverlage Stuttgart GmbH & Co. KG
Stuttgart · New York

 
  • Literatur

  • 1 Bowden Davies KA, Sprung VS, Norman JA. et al. Short-term decreased physical activity with increased sedentary behaviour causes metabolic derangements and altered body composition- effects in individuals with and without a first-degree relative with type 2 diabetes. Diabetologia 2018; 61 (06) 1282-1294
  • 2 Robinson D, Milne C. Medicine at the 2000 Sydney Olympic Games: The New Zealand Health Team. Br J Sports Med 2002; 36 (03) 229
  • 3 Valtonen M, Waris M, Vuorinen T. et al. Common cold in Team Finland during 2018 Winter Olympic Games (PyeongChang): Epidemiology, diagnosis including molecular point-of-care testing (POCT) and treatment. Br J Sports Med 2019; 53 (17) 1093-1098
  • 4 Walsh NP, Oliver SJ. Exercise, immune function and respiratory infection: An update on the influence of training and environmental stress. Immunol Cell Biol 2016; 94 (02) 132-139
  • 5 Von Schacky C, Kemper M, Haslbauer R. et al. Low omega-3 index in 106 German elite winter endurance athletes: A pilot study. Int J Sport Nutr Exerc Metab 2014; 24 (05) 559-564
  • 6 Krüger K, Lechtermann A, Fobker M. et al. Exercise-induced redistribution of T lymphocytes is regulated by adrenergic mechanisms. Brain Behav Immun 2008; 22 (03) 324-338
  • 7 Campbell JP, Riddel NE, Burns VE. et al. Acute exercise mobilises CD8+ T lymphocytes exhibiting an effector-memory phenotype. Brain Behav Immun 2009; 23 (06) 767-775
  • 8 Nunes-Silva A, Bernardes PTT, Rezende BM. et al. Treadmill exercise induces neutrophil recruitment into muscle tissue in a reactive oxygen species-dependent manner. An intravital microscopy study. PLOS One 2014; 9 (05) e96464
  • 9 Wu J, Weisshaar N, Hotz-Wagenblatt A. et al. Skeletal muscle antagonizes antiviral CD8+ T cell exhaustion. Sci Adv 2020; 6 (24) eaba3458
  • 10 Lee JY, Paik IY, Kim JY. Voluntary exercise reverses immune aging induced by oxidative stress in aging mice. Exp Gerontol 2019; 115: 148-154
  • 11 Duggal NA, Niemiro G, Harridge SDR. et al. Can physical activity ameliorate immunosenescence and thereby reduce age-related multi-morbidity?. Nat Rev Immunol 2019; 19 (09) 563-572
  • 12 Zimmer P, Bloch W, Schenk A. et al. High-intensity interval exercise improves cognitive performance and reduces matrix metalloproteinases-2 serum levels in persons with multiple sclerosis: A randomized controlled trial. Mult Scler 2018; 24 (12) 1635-1644
  • 13 Xie Y, Zhengyi L, Wang Y. et al. Effects of moderate – versus high – intensity swimming training on inflammatory and CD4 + T cell subset profiles in experimental autoimmune encephalomyelitis mice. J Neuroimmunol 2019; 328: 60-67
  • 14 Dos Santos JR, Bortolanza M, Duarte Ferrari G. et al. One-week high-intensity interval training increases hippocampal plasticity and mitochondrial content without changes in redox state. Antioxidants (Basel) 2020; 9 (05) 445
  • 15 Dhabhar FS, Malarkey WB, Neri E. et al. Stress-induced redistribution of immune cells – from barracks to boulevards to battlefields. DOI: doi: 10.1016/j.psyneuen.2012.05.008