Laryngorhinootologie 2020; 99(11): 772-778
DOI: 10.1055/a-1208-5284
Übersicht

Übersicht und aktuelle Empfehlung zur Therapie des Rhinophyms

A systematic review and current recommendation for treatment of rhinophyma
Jamal Huseynov
1   HNO-Heilkunde, Kopf- und Halschirurgie, Schwarzwald-Baar-Klinikum Villingen-Schwenningen GmbH, Villingen-Schwenningen, Germany
,
Christian Mozet
2   HNO, Schwarzwald-Baar-Klinikum Villingen-Schwenningen GmbH, Villingen-Schwenningen, Germany
› Author Affiliations

Zusammenfassung

Als Rhinophym wird eine benigne Hautveränderung der äußeren Nase bezeichnet, die durch eine Hypertrophie der Talgdrüsen gekennzeichnet ist. Betroffen sind meistens männliche Kaukasier zwischen der 5. und 7. Lebensdekade. Die Ätiologie der Erkrankung ist bisher nicht vollständig geklärt, sie wird jedoch als Spätstadium der Acne rosacea betrachtet. Ein äthyltoxischer Zusammenhang, wie bisher vermutet wurde, ist bis dato nicht belegt worden. Der Artikel gibt einen Überblick über mögliche operative und konservative Therapieansätze. Die chirurgische Therapie stellt dabei den Goldstandard dar. Dabei erweist sich der Einsatz der Elektroschlinge zur subtilen Resektion und die Verwendung der monopolaren Kugel zur Feinmodulation als besonders vorteilhaft. Aufgrund einer möglichen Koinzidenz des Basalzell- oder Plattenepithelkarzinoms im Rhinophymgewebe, erscheint eine histopathologische Aufarbeitung des abgetragenen Gewebes sinnvoll.

Abstract

Rhinophyma is a benign disease involving the skin of the nose, which is characterized by skin thickening and hypertrophy of the sebaceous glands and connective tissue. It occurs predominantly by Caucasians in their fifth to seventh life decades and is 12–30 times more likely to affect males. The etiology and pathogenesis of Rhinophyma remains unclear, however it is generally stated to be the final stage of rosacea. A causative relationship between rhinophyma and alcohol consumption has not yet been proven. This review highlights the treatment options of rhinophyma. Surgery is gold standard for management of advanced rhinophyma. Each technique has pros and cons, but using surgical instruments with monopolar energy as loop and ball electrode seem to combine several goals best – first of all simultaneous removal and hemostasis followed by nasal contour refinement. Due to possible coincidence of skin cancer such as a basal- or squamous cell carcinoma, histopathological examination of all removed tissue is recommended.



Publication History

Received: 18 September 2019

Accepted: 25 June 2020

Article published online:
27 October 2020

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
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  • Literatur

  • 1 Clark DP, Hanke CW. Electrosurgical treatment of rhinophyma. J Am Acad Dermatol 1990; 22 (05) 831-837 . doi:10.1016/0190-9622(90)70115-X
  • 2 Clarós P, Sarr MC, Nyada FB. et al Rhinophyma: Our experience based on a series of 12 cases. Eur Ann Otorhinolaryngol Head Neck Dis 2018; 135 (01) 17-20 . doi:10.1016/j.anorl.2017.08.005
  • 3 von Hebra F. Atlas Der Hautkrankheiten. Wein, Germany: Braunmuller; 1856
  • 4 van Zuuren EJ. Rosacea. Solomon CG, ed. N Engl J Med 2017; 377 (18) 1754-1764 . doi:10.1056/NEJMcp1506630
  • 5 Sadick H, Riedel F, Bran G. Rhinophym bei Rosazea: Was leistet die operative Therapie?. Hautarzt 2011; 62 (11) 834-841 . doi:10.1007/s00105-011-2146-5
  • 6 Hoasjoe DK, Stucker FJ. Rhinophyma: review of pathophysiology and treatment. J Otolaryngol 1995; 24 (01) 51-56
  • 7 Little S, Stucker F, Compton A. et al Nuances in the Management of Rhinophyma. Facial Plast Surg 2012; 28 (02) 231-237 . doi:10.1055/s-0032-1309304
  • 8 Rebora A. Rosacea. J Invest Dermatol 1987; 88 (Suppl. 03) 56s-60s . doi:10.1111/1523-1747.ep12468949
  • 9 Jansen T, Plewig G. Clinical and Histological Variants of Rhinophyma, Including Nonsurgical Treatment Modalities. Facial Plast Surg 1998; 14 (04) 241-253 . doi:10.1055/s-2008-1064456
  • 10 Krausz AE, Goldberg DJ, Ciocon DH. et al Procedural management of rhinophyma: A comprehensive review. J Cosmet Dermatol 2018; 17 (06) 960-967 . doi:10.1111/jocd.12770
  • 11 Antunes M, Frasson G, Ottaviano G. et al Giant rhinophyma in low-resource setting: a case report. Int J Dermatol 2017; 56 (08) 875-877 . doi:10.1111/ijd.13682
  • 12 Rohrich RJ, Griffin JR, Adams WP. Rhinophyma: Review and Update. Plast Reconstr Surg 2002; 110 (03) 860-870 . doi:10.1097/00006534-200209010-00023
  • 13 Curnier A, Choudhary S. Rhinophyma: Dispelling the Myths. Plast Reconstr Surg 2004; 114 (02) 351-354 . doi:10.1097/01.PRS.0000131875.67987.69
  • 14 Fink C, Lackey J, Grande DJ. Rhinophyma: A Treatment Review. Dermatol Surg 2018; 44 (02) 275-282 . doi:10.1097/DSS.0000000000001406
  • 15 Elliott RA, Hoehn JG, Stayman JW. Rhinophyma: Surgical Refinements. Ann Plast Surg 1978; 1 (03) 298-301 . doi:10.1097/00000637-197805000-00009
  • 16 Wiemer DR. Rhinophyma. Clin Plast Surg 1987; 14 (02) 357-365
  • 17 Acker DW, Helwig EB. Rhinophyma with carcinoma. Arch Dermatol 1967; 95 (03) 250-254
  • 18 Aloi F, Tomasini C, Soro E. et al The clinicopathologic spectrum of rhinophyma. J Am Acad Dermatol 2000; 42 (03) 468-472 . doi:10.1016/S0190-9622(00)90220-2
  • 19 Jung H. Rhinophyma: Plastic Surgery, Rehabilitation, and Long-Term Results. Facial Plast Surg 1998; 14 (04) 255-278 . doi:10.1055/s-2008-1064457
  • 20 Schweinzer K, Kofler L, Spott C. et al Surgical treatment of rhinophyma: experience from a German cohort of 70 patients. Eur J Dermatol 2017; 27 (03) 281-285 . doi:10.1684/ejd.2017.2987
  • 21 Diffenbach J. Die operative Chirurgie. Brockhaus, Leipzig 1845; 1: 373
  • 22 Joseph J. Nasenplastik Und Sonstige Gesichtsplastik Nebst Mammaplastik. Leipzig: Curt Kabitzsche; 1931
  • 23 Plenk HP. Rhinophyma, Associated with Carcinoma, Treated Successfully with Radiation. Plast Reconstr Surg 1995; 95 (03) 559-562 . doi:10.1097/00006534-199503000-00020
  • 24 Sonnex TS, Dawber RPR. Rhinophyma-treatment by liquid nitrogen spray cryosurgery. Clin Exp Dermatol 1986; 11 (03) 284-288 . doi:10.1111/j.1365-2230.1986.tb00460.x
  • 25 Nolan JO. Cryosurgical treatment of rhinophyma. Case report. Plast Reconstr Surg 1973; 52 (04) 437-438
  • 26 Fisher WJ. Rhinophyma: its surgical treatment. Plast Reconstr Surg 1970; 45 (05) 466-470 . doi:10.1097/00006534-197005000-00009
  • 27 Farrior RT. Dermabrasion in facial surgery. The Laryngoscope 1985; 95 (05) 534-545 . doi:10.1288/00005537-198505000-00004
  • 28 Hom DB, Harmon J. Dermabrasion for Scars and Wire Loop Electrocautery for Rhinophyma. Facial Plast Surg 2019; 35 (03) 267-273 . doi:10.1055/s-0039-1688845
  • 29 Gupta S, Handa S, Saraswat A. et al Conventional Cold Excision Combined with Dermabrasion for Rhinophyma. J Dermatol 2000; 27 (02) 116-120 . doi:10.1111/j.1346-8138.2000.tb02132.x
  • 30 Newberry C, Thomas J, Cerrati E. Facial Scar Improvement Procedures. Facial Plast Surg 2018; 34 (05) 448-457 . doi:10.1055/s-0038-1669400
  • 31 Aferzon M, Millman B. Excision of Rhinophyma With High-Frequency Electrosurgery. Dermatol Surg 2002; 28 (08) 735-738 . doi:10.1046/j.1524-4725.2002.02013.x
  • 32 Greenbaum SS, Krull EA, Watnick K. Comparison of CO2 laser and electrosurgery in the treatment of rhinophyma. J Am Acad Dermatol 1988; 18 (02) 363-368 . doi:10.1016/S0190-9622(88)70053-5
  • 33 Prado R, Funke A, Brown M. et al Treatment of Severe Rhinophyma Using Scalpel Excision and Wire Loop Tip Electrosurgery. Dermatol Surg 2013; 39 (05) 807-810 . doi:10.1111/dsu.12193
  • 34 Baró CJ, Gómez R, Serrat A. CO2 Laser for the Treatment of Rhinophyma. Acta Otorrinolaringol Engl Ed 2015; 66 (01) 61-62 . doi:10.1016/j.otoeng.2013.06.017
  • 35 Bassi A, Campolmi P, Dindelli M. et al. Laser surgery in rhinophyma. G Ital Dermatol E Venereol Organo Uff Soc Ital Dermatol E Sifilogr 2016; 151 (01) 9-16
  • 36 Shapshay SM, Strong MS, Anastasi GW. et al Removal of Rhinophyma With the Carbon Dioxide Laser: A Preliminary Report. Arch Otolaryngol – Head Neck Surg 1980; 106 (05) 257-259 . doi:10.1001/archotol.1980.00790290009004
  • 37 el-Azhary RA, Roenigk RK, Wang TD. Spectrum of results after treatment of rhinophyma with the carbon dioxide laser. Mayo Clin Proc 1991; 66 (09) 899-905 . doi:10.1016/s0025-6196(12)61576-6
  • 38 Singh S, Peterson JD, Friedman PM. Management of Mild to Moderate Rhinophyma Using Ablative Fractional Photothermolysis. Dermatol Surg 2013; 39 (07) 1110-1113 . doi:10.1111/dsu.12222