Z Gastroenterol 2021; 59(09): 991-994
DOI: 10.1055/a-1484-1544
Kommentiertes Referat

Evaluation und Notwendigkeit einer Anpassung des MELD Scores in der Eurotransplantregion

Isabella Wiest
1   II. Medizinische Klinik, Universitätsklinikum Mannheim, Medizinische Fakultät Mannheim, Universität Heidelberg, Mannheim
,
Ana Paula Barreiros
2   Deutsche Stiftung Organtransplantation (DSO), Region Mitte, Mainz
,
Hans Jürgen Schlitt
3   Klinik und Poliklinik für Chirurgie, Universitätsklinikum Regensburg, Regensburg
,
Matthias Philip Ebert
1   II. Medizinische Klinik, Universitätsklinikum Mannheim, Medizinische Fakultät Mannheim, Universität Heidelberg, Mannheim
4   Klinische Kooperationseinheit Healthy Metabolism, Zentrum für Präventivmedizin und Digitale Gesundheit Baden-Württemberg, Medizinische Fakultät Mannheim Universität Heidelberg, Mannheim
,
Andreas Teufel Prof. Dr. Dr.
4   Klinische Kooperationseinheit Healthy Metabolism, Zentrum für Präventivmedizin und Digitale Gesundheit Baden-Württemberg, Medizinische Fakultät Mannheim Universität Heidelberg, Mannheim
5   II. Medizinische Klinik, Sektion Hepatologie, Universitätsklinikum Mannheim, Medizinische Fakultät Mannheim, Universität Heidelberg, Mannheim
› Author Affiliations

Publikationen

  1. Validation of the Model for End-stage Liver Disease sodium (MELD-Na) score in the Eurotransplant region. B. F. J. Goudsmit, H. Putter, M. E. Tushuizen, J. de Boer, S. Vogelaar, I. P. J. Alwayn, et al. Am J Transplant 2021 Vol. 21 Issue 1 Pages 229–240, Accession Number: 32529758 PMCID: PMC7818465 DOI: 10.1111/ajt.16142

  2. Refitting the Model for End-stage Liver Disease for the Eurotransplant region. B. F. J. Goudsmit, H. Putter, M. E. Tushuizen, S. Vogelaar, J. Pirenne, I. P. J. Alwayn, et al. Hepatology 2020, Accession Number: 33301607 DOI: 10.1002/hep.31677



Publication History

Article published online:
10 September 2021

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  • Literatur

  • 1 DSO. DSO. Jahresbericht. Organspende und Transplantation in Deutschland. 2019
  • 2 Ginés P, Quintero E, Arroyo V. et al. Compensated cirrhosis: natural history and prognostic factors. Hepatology (Baltimore, Md) 1987; 7 (01) 122-128w
  • 3 D’Amico G, Garcia-Tsao G, Pagliaro L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. Journal of hepatology 2006; 44 (01) 217-231
  • 4 Child CG, Turcotte JG. Surgery and portal hypertension. Major Probl Clin Surg 1964; 1: 1-85
  • 5 Jalan R, Arroyo V. Organ allocation for patients with acute-on-chronic liver failure: Time to look beyond MELD-sodium?. Journal of hepatology 2020; 73 (06) 1316-1318
  • 6 Huang HC, Lee FY, Huo TI. Major adverse events, pretransplant assessment and outcome prediction. Journal of gastroenterology and hepatology 2009; 24 (11) 1716-1724
  • 7 Malinchoc M, Kamath PS, Gordon FD. et al. A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts. Hepatology (Baltimore, Md) 2000; 31 (04) 864-871
  • 8 Kamath PS, Wiesner RH, Malinchoc M. et al. A model to predict survival in patients with end-stage liver disease. Hepatology (Baltimore, Md) 2001; 33 (02) 464-470
  • 9 Wiesner RH, McDiarmid SV, Kamath PS. et al. MELD and PELD: application of survival models to liver allocation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2001; 7 (07) 567-580
  • 10 Merion RM, Schaubel DE, Dykstra DM. et al. The survival benefit of liver transplantation. Am J Transplant 2005; 5 (02) 307-313
  • 11 Goudsmit BFJ, Putter H, Tushuizen ME. et al. Validation of the Model for End-stage Liver Disease sodium (MELD-Na) score in the Eurotransplant region. Am J Transplant 2021; 21 (01) 229-240
  • 12 Godfrey EL, Malik TH, Lai JC. et al. The decreasing predictive power of MELD in an era of changing etiology of liver disease. Am J Transplant 2019; 19 (12) 3299-3307
  • 13 Gómez MP, Irazábal Jr, Manyalich M. INTERNATIONAL REGISTRY IN ORGAN DONATION AND TRANSPLANTATION (IRODAT)–2019 WORLDWIDE DATA. Transplantation 2020; 104 (03) S272
  • 14 Tschuor C, Ferrarese A, Kuemmerli C. et al. Allocation of liver grafts worldwide – Is there a best system?. Journal of hepatology 2019; 71 (04) 707-718
  • 15 Artru F, Samuel D. Approaches for patients with very high MELD scores. JHEP reports : innovation in hepatology 2019; 1 (01) 53-65
  • 16 Nagai S, Chau LC, Schilke RE. et al. Effects of Allocating Livers for Transplantation Based on Model for End-Stage Liver Disease-Sodium Scores on Patient Outcomes. Gastroenterology 2018; 155 (05) 1451-1462.e1453
  • 17 Goudsmit BFJ, Putter H, Tushuizen ME. et al. Refitting the Model for End-stage Liver Disease for the Eurotransplant region. Hepatology (Baltimore Md) 2020;
  • 18 Kim TY, Kim MY, Sohn JH. et al. Sarcopenia as a useful predictor for long-term mortality in cirrhotic patients with ascites. J Korean Med Sci 2014; 29 (09) 1253-1259
  • 19 Thomas PG. MELD-based organ allocation policy: Time for change. Am J Transplant 2018; 18 (11) 2833
  • 20 van Vugt JLA, Alferink LJM, Buettner S. et al. A model including sarcopenia surpasses the MELD score in predicting waiting list mortality in cirrhotic liver transplant candidates: A competing risk analysis in a national cohort. Journal of hepatology 2018; 68 (04) 707-714
  • 21 Luo X, Massie AB, Gentry SE. et al. MELD allocation system: There is always space to improve. Am J Transplant 2018; 18 (11) 2834-2835
  • 22 Hernaez R, Liu Y, Kramer JR. et al. Model for end-stage liver disease-sodium underestimates 90-day mortality risk in patients with acute-on-chronic liver failure. Journal of hepatology 2020; 73 (06) 1425-1433
  • 23 Abdallah MA, Kuo YF, Asrani S. et al. Validating a novel score based on interaction between ACLF grade and MELD score to predict waitlist mortality. Journal of hepatology 2020;
  • 24 Machicao VI. Model for End-Stage Liver Disease-Sodium Score: The Evolution in the Prioritization of Liver Transplantation. Clin Liver Dis 2017; 21 (02) 275-287
  • 25 Bundesärztekammer. Richtlinien zur Organtransplantation gem. §16 TPG. Richtlinie gemäß § 16 Abs. 1 S. 1 Nrn. 2 u. 5 TPG für die Wartelistenführung und Organvermittlung zur Lebertransplantation. Deutsches Ärzteblatt. 2016
  • 26 Stine JG, Stukenborg GJ, Wang J. et al. Liver transplant candidates have impaired quality of life across health domains as assessed by computerized testing. Annals of hepatology 2020; 19 (01) 62-68
  • 27 Vagefi PA, Bertsimas D, Hirose R. et al. The rise and fall of the model for end-stage liver disease score and the need for an optimized machine learning approach for liver allocation. Curr Opin Organ Transplant 2020; 25 (02) 122-125
  • 28 Bundesregierung. Entwurf eines Gesetzes zur Errichtung eines Transplantationsregisters. 2016
  • 29 Harries L. Versorgungsstrukturen im Transplantationswesen: Analyse der Versorgungspfade und Kosten von lebertransplantierten Patienten: Medizinische Hochschule Hannover. 2018