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Combined endoscopic ultrasound-guided gastrojejunostomy and anterograde biliary stenting
Malignant involvement of the second portion of the duodenum and surrounding structures can create therapeutic challenges. We report a case of combined endoscopic ultrasound (EUS)-guided gastrojejunostomy (GJ) and anterograde biliary stenting in a patient with an infiltrative porta hepatis mass causing gastric outlet obstruction (GOO) and biliary obstruction.
An 83-year-old woman with gastric adenocarcinoma was found to have a malignant biliary obstruction due to infiltration of the porta hepatis and common bile duct (CBD) on magnetic resonance cholangiopancreatography ([Fig. 1]). Endoscopic retrograde cholangiopancreatography was attempted, but there was clear evidence of an evolving GOO with malignant involvement of the ampullary region.
We proceeded with combined EUS-GJ and EUS-guided gastrohepatic access with anterograde biliary stenting. The endoscope was advanced beyond the obstruction, and the duodenum distal to the ligament of Treitz was distended with saline, contrast, and methylene blue. The jejunum was identified on EUS and confirmed with needle aspiration. A 15-mm AXIOS electrocautery-enhanced lumen-apposing metal stent (Boston Scientific, Marlborough, Massachusetts, USA) was deployed under EUS guidance; egress of methylene blue confirmed successful placement.
To address the biliary obstruction, a dilated left hepatic biliary radical was identified and punctured with a 19-gauge needle. Cholangiogram was notable for CBD stricture. A 0.025-inch guidewire was advanced anterograde into the duodenum. To facilitate anterograde stent deployment, and because there are no cystotomes readily available in the USA, the AXIOS catheter was reset and used over the wire to create a tract. This allowed for anterograde placement of an uncovered 10 × 80-mm biliary metal stent across the biliary stricture ([Fig. 2]). The puncture site was closed with an over-the-scope clip ([Video 1]).
Video 1 Combined endoscopic ultrasound-guided gastrojejunostomy and anterograde biliary stenting for treatment of malignant obstruction involving the duodenum and bile duct.
The patient tolerated the procedure without complications and was discharged to a hospice. This report highlights how EUS can be used for a combined biliary and luminal obstruction, with the reuse of an electrocautery-enhanced catheter for stent delivery.
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The authors declare that they have no conflict of interest.
Article published online:
18 June 2021
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