Endoscopy 2022; 54(06): E318-E319
DOI: 10.1055/a-1527-7600
E-Videos

Traction-assisted endoscopic submucosal dissection of a duodenal gastrointestinal stromal tumor

Francisco Baldaque-Silva
1   Division of Medicine, Department of Upper Gastrointestinal Diseases, Karolinska University Hospital and Karolinska Institute, Stockholm, Sweden
,
Naining Wang
2   Department of Pathology, Karolinska University Hospital and Karolinska Institute, Stockholm, Sweden
,
Ioannis Rouvelas
3   Division of Surgery, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institute, Stockholm, Sweden
,
Masami Omae
1   Division of Medicine, Department of Upper Gastrointestinal Diseases, Karolinska University Hospital and Karolinska Institute, Stockholm, Sweden
› Author Affiliations
 

A 70-year-old woman with a gastric adenocarcinoma and a subepithelial lesion in the distal descending duodenum ([Fig. 1]) was referred to us. On endoscopic ultrasound (EUS), a 15-mm hypoechoic, regular, and homogeneous lesion engaging the muscularis propria was observed ([Fig. 2]). Histopathology analysis of the fine-needle biopsy showed a gastrointestinal stromal tumor (GIST) with a low proliferative index. After discussion in a multidisciplinary team conference and on patient consent, an endoscopic submucosal dissection (ESD) and gastrectomy were performed in the same session.

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Fig. 1 Subepithelial lesion in the distal descending duodenum covered by normal mucosa.
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Fig. 2 Endoscopic ultrasound showing a 15-mm hypoechoic, regular, and homogeneous lesion engaging the muscularis propria.

In order to facilitate access to the submucosa during ESD, we applied a traction system using a dental floss ring and two clips ([Fig. 3]). This system enabled quick, safe, and complete resection with full control of the dissection plane ([Fig. 4], [Video 1]). The GIST was resected en bloc and the wall defect was fully closed using eight metallic clips and an endoloop ([Fig. 5]). There were no adverse events during the procedure. Postoperatively, the patient developed mild abdominal pain, which was easily controlled with painkillers, and oral intake was restarted on day 3. The patient was re-admitted at 2 months owing to fever caused by a retroperitoneal fluid collection that was treated with antibiotherapy and EUS drainage; she remained asymptomatic at the 3-month follow-up.

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Fig. 3 Traction system using a dental floss ring and two conventional clips.
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Fig. 4 Traction system enabling full control of the dissection plane.

Video 1 Endoscopic submucosal dissection of a gastrointestinal stromal tumor using a traction system.


Quality:
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Fig. 5 Closure of the wall defect after tumor resection using eight metallic clips and an endoloop.

ESD has been increasingly used for the treatment of duodenal epithelial [1] and subepithelial [2] [3] lesions. Endoscopic treatment of GISTs is controversial due to the need for complete resection and associated risks. Small series of gastric GIST ESD were described, but only few cases of GIST ESDs were reported [4] and none with this technique. Several traction devices may be used for ESD [5], but this GIST was located in the distal duodenum, precluding the use of most of them. This case also highlights the need for long and close follow-up of these patients.

Endoscopy_UCTN_Code_CCL_1AB_2AZ_3AB

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Competing interests

The authors declare that they have no conflict of interest.


Corresponding author

Francisco Baldaque-Silva, MD
Department of Upper Gastrointestinal Diseases
Karolinska University Hospital
Huddinge
141 86 Stockholm
Sweden   

Publication History

Article published online:
09 July 2021

© 2021. Thieme. All rights reserved.

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Zoom Image
Fig. 1 Subepithelial lesion in the distal descending duodenum covered by normal mucosa.
Zoom Image
Fig. 2 Endoscopic ultrasound showing a 15-mm hypoechoic, regular, and homogeneous lesion engaging the muscularis propria.
Zoom Image
Fig. 3 Traction system using a dental floss ring and two conventional clips.
Zoom Image
Fig. 4 Traction system enabling full control of the dissection plane.
Zoom Image
Fig. 5 Closure of the wall defect after tumor resection using eight metallic clips and an endoloop.