Sport reduziert den diabetesassoziierten Verlust kognitiver Fähigkeiten bei Typ-2-Diabetes-Patienten

Zusammenfassung

Kognitive Defizite entwickeln sich bei T2D-Patienten häufig auf dem Boden metabolischer Störungen. Neben den eher mild ausfallenden, aber klinisch relevanten diabetesassoziierten kognitiven Dysfunktionen geht T2 D ebenfalls mit einem erhöhten Risiko für Demenz verschiedener Ursachen einher. Die zugrunde liegenden Mechanismen, die zu einer diabetesassoziierten kognitiven Dysfunktion führen, sind nicht vollständig geklärt. Trainingsinterventionen bieten die Möglichkeit, mögliche metabolische Risikofaktoren zu verringern und gleichzeitig dadurch die diabetesassoziierten kognitiven Verschlechterungen zu reduzieren. Unklar ist allerdings noch, welche Trainingsart und -intensität den größten gesundheitlichen Nutzen bringt, da bisherige Studienergebnisse wegen unterschiedlicher Kohorten, Interventionsmethoden und Interventionsdauern schwer zu vergleichen sind.

Abstract

Cognitive dysfunction often develops due to diabetes-related metabolic complications. Besides mild cognitive impairment, diabetes also increases the risk for dementia. However, the relevant mechanisms that trigger cognitive dysfunction in diabetes mellitus are yet to be understood in its entirety. As a matter of fact, exercise training improves metabolic markers, and in this way can contribute to cognitive enhancement. Nevertheless, the results of the given reports are poorly comparable, since study groups, length and methods of interventions are inconsistent. Thus, concrete recommendations regarding type and strength of exercise are not determined yet.

Schlüsselwörter

Kognitive Störungen - Demenz - Diabetes mellitus Typ 2 - körperliches Training

Key words

cognitive impairment - dementia - type 2 diabetes mellitus - physical exercise

Publication History

Received: 23 April 2021

Accepted: 08 June 2021

Article published online:
05 July 2021

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