A 39-year-old man underwent a distal spleno-pancreatectomy and colonic resection for
a tail pancreatic cancer infiltrating the colonic splenic flexure. Five days after
surgery, the patient experienced fever and abdominal pain. A computed tomography (CT)
scan showed a 10-cm intra-abdominal collection with free air bubbles inside; oral
contrast-medium intake revealed a passage from the colon to the abdominal collection,
highly suspicious of an anastomotic leak ([Fig. 1]).
Fig. 1 Computed tomography scan showing an extra-luminal contrast-medium passage (red arrow)
from the left colonic anastomotic region to the intra-abdominal collection located
in the splenic loggia.
Endoscopy confirmed a wide anastomotic leakage with access to a peri-anastomotic cavity
([Fig. 2 a, b]) and we decided to attempt endoscopic internal drainage in order to avoid a new
surgical procedure.
Fig. 2 Endoscopic views. a Leak (asterisks) of the colo-colonic anastomosis with an orifice (red arrow). b Wide peri-anastomotic cavity accessed through the orifice.
Under endoscopic view and fluoroscopic guidance, two double-pigtail plastic stents
(10-Fr/10-cm and 7-Fr/7-cm, Boston Scientific, Massachusetts, USA) were placed across
the leak orifice ([Video 1]) with one pigtail tip of each stent located inside the cavity. A CT scan 24 hours
later confirmed the correct placement of the two stents.
Video 1 Endoscopic internal drainage using double-pigtail stent placement to manage proximal
colo-colonic anastomotic leakage. This approach works by promoting collapse of the
collection, granulation-tissue formation and re-epithelization of the leak orifice
Follow-up CT scans showed a progressive reduction in the collection’s size up to 2 cm
at 5 weeks, so stent removal was planned. Endoscopy showed a closure of the anastomotic
leak and a single stent “in situ” that was removed with a forceps. The next CT scan
confirmed the complete collapse of peri-anastomotic collection ([Fig. 3]). After 6 months, the colo-colonic anastomosis appeared endoscopically regular with
a complete closure of the leakage ([Fig. 4]).
Fig. 3 Computed tomography scan showing a complete collapse of the peri-anastomotic collection
after stent removal.
Fig. 4 Endoscopic view of regular colo-colonic anastomosis with a complete closure of the
leak orifice (arrow) at 6-month follow-up.
Endoscopy is emerging as a first-line approach over surgery for management of post-operative
gastrointestinal leaks and fistulae [1]. While endoluminal vacuum therapy is reported as an effective method for management
of colo-rectal anastomotic leakages [2], endoscopic internal drainage by double-pigtail stent placement is described as
a conservative treatment of leaks and fistulas after upper gastrointestinal surgery,
especially in the bariatric setting [3]
[4]
[5]. The application of endoscopic internal drainage technique in this case allowed
us to successfully and conservatively manage a proximal colo-colonic anastomotic leakage
without needing a protective ileostomy or an additional surgical procedure.
Endoscopy_UCTN_Code_TTT_1AQ_2AG
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