Validierung des telemetrischen BioHarness^TM 3-Brustgurtes für die Messung der Herzratenvariabilität (HRV) bei Schweinen

Zusammenfassung

Ziel Ziel dieser klinischen Studie war es, die Messgenauigkeit des telemetrischen, für den Menschen konzipierten und auf die Analyse der Herzratenvariabilität (HRV) spezialisierten Brustgurtes BioHarness^TM 3 (Zephyr Technology, Medtronic, Annapolis, USA) für die Tierart Schwein zu überprüfen.

Methoden Hierzu wurden die Abstände der R-Zacken (RR-Abstände) des BioHarness^TM 3 Elektrokardiogramms (EKG) mit denen des etablierten, telemetrischen EKG-Gerätes Televet^®100 (Engel Engineering GmbH, Heusenstamm, Deutschland) verglichen. Die Messungen erfolgten wegen des Risikos der Ablösung der Klebeelektroden beim Televet^®100 unter Allgemeinanästhesie, um eine kontinuierliche Datenaufzeichnung zu gewährleisten. Bei zeitgleichem Start der Geräte wurden 6 Messdurchgänge à 5 Minuten in Folge bei 5 männlichen Aufzuchtschweinen durchgeführt. Nach Artefaktkorrektur bzw. -bereinigung konnten insgesamt 5321 RR-Messdatenpaare im dreistelligen Bereich (ms) statistisch analysiert werden.

Ergebnisse Nach den Ergebnissen der Konkordanz-Korrelations-Analyse nach Lin (Korrelationskoeffizient 0,95) und der Bland-Altman-Analyse (RR-Abstandsdifferenz + 0,3 ms) ergab sich eine sehr gute Übereinstimmung beider Messgeräte.

Schlussfolgerung Der BioHarness-Brustgurt kann demnach am Schwein für eine kabellose HRV-Analyse genutzt werden, wie dies in einer Folgestudie auch an nicht betäubten Schweinen gezeigt werden konnte.

Abstract

Objective The aim of this clinical study was to determine whether the telemetric BioHarness 3.0^TMchest strap (Zephyr Technology, Medtronic, Annapolis, USA), designed for use in humans and specialized for heart rate variability (HRV) analysis, could be used to accurately measure Heart Rate Variability (HRV) in pigs.

Methods The R-wave intervals (RR-intervals) of the BioHarness 3.0^TM electrocardiogram (ECG) were compared with those of the widely used telemetric ECG Televet^®100 device (Engel Engineering GmbH, Heusenstamm, Germany). Measurements were performed under general anesthesia, to ensure continuous data collection due to the risk of detachment in adhesive electrodes of the Televet^®100. The 2 devices were started simultaneously and measurements were taken 6 times in a row for 5 minutes, respectively. The data were collected from 5 male growing pigs. Following artifact correction resp. deletion 5321 RR paired data within a 3 digit range (ms) were analyzed statistically.

Results The Lin Concordance-Correlation-Analysis after Lin (correlation coefficient 0.95), and the Bland-Altman-Analysis (RR distance differences + 0.3 ms) demonstrated a very good measurement compliance.

Conclusion This data suggests the BioHarness chest strap may be used for wireless HRV analysis in pigs as was shown in a follow up study in non-anesthetized pigs.

Schlüsselwörter

Schwein - Herz - Herzfrequenz - kabellose Messung - Methodenvergleich

Key words

Swine - heart - heart rate - cordless measuring - method comparison

Publication History

Received: 04 June 2021

Accepted: 30 November 2021

Article published online:
02 March 2022

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