Synlett 2022; 33(10): 983-987
DOI: 10.1055/a-1801-4344
letter

Synthesis of the Icetexane Diterpenoids (±)-Rosmaridiphenol, (±)-Pisiferin, and (±)-Barbatusol from Abietane

Thuy Quynh Le
,
JuHui Lee
,
Chang Ho Oh
This research was supported by a Basic Science Research Program through the National Research Foundation of Korea (NRF), funded by the Ministry of Education (NRF-2021R1F1A1049992).


Abstract

We report the rearrangement of abietane core with trifluoromethanesulfonic anhydride in pyridine to afford the icetexane core, a key intermediate for total syntheses of the structurally intriguing and biologically active compounds (±)-barbatusol, (±)-rosmaridiphenol, and (±)-pisiferin.

Supporting Information



Publikationsverlauf

Eingereicht: 08. Februar 2022

Angenommen nach Revision: 17. März 2022

Accepted Manuscript online:
17. März 2022

Artikel online veröffentlicht:
12. April 2022

© 2022. Thieme. All rights reserved

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