„Hyposplenie“, eine weitgehend unerkannte Immunschwäche: Ist die Sonografie hilfreich?

Zusammenfassung

Das Immundefizienzsyndrom der funktionellen Hyposplenie/Asplenie ist weitgehend unerkannt. Die Goldstandardprozedur stellt die Technetium-99m-Szintigrafie von hitzedenaturierten Erythrozyten (TSZ) sowie der Nachweis von pitted Erythrozyten oder Howell-Jolly-Körperchen (HJB) dar. Erste Arbeiten weisen darauf hin, dass dieses Krankheitsbild mit einer kleinen Milz assoziiert ist. Ziel der vorliegenden Übersicht ist es, den Stellenwert der B-Bild-Sonografie und der kontrastunterstützten Sonografie bei der Immunschwäche der Hyposplenie darzustellen.

Abstract

The immunodeficiency syndrome of functional hyposplenia/asplenia is frequently unrecognized. The gold standard procedure for the diagnosis of this disease is technetium-99m scintigraphy of heat-denatured erythrocytes and the detection of pitted erythrocytes or Howell–Jolly bodies. Initial work suggests that this clinical presentation is associated with a small spleen. The aim of this review is to describe the value of B-mode and contrast-enhanced ultrasound in the identification of immunodeficiency caused by functional hyposplenism.

Schlüsselwörter

Hyposplenie - Asplenie - Ultraschall - Milz - Howell-Jolly-Körperchen

Keywords

hyposplenism - asplenia - ultrasound - spleen - Howell-Jolly bodies

Publication History

Received: 08 March 2022

Accepted: 13 July 2022

Article published online:
22 November 2022

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